White Cell Abnormalities Chapter 10 Test Questions & Answers - Test Bank | Hematology in Practice 3e by Betty Ciesla by Betty Ciesla. DOCX document preview.
Chapter 10. Abnormalities of White Cells: Quantitative, Qualitative, and the Lipid Storage Diseases
Multiple Choice
1. A 17-year-old boy is admitted to the hospital with a fever of unknown origin. His WBC count is 20.0 × 109/L. All of the following can be seen on his peripheral smear except:
A. Toxic granulation
B. Reactive monocytes
C. Increased band neutrophils
D. Döhle bodies
L.O. 10.1 & 10.2 & 10.6
2. A typical blood picture in infectious mononucleosis is an absolute:
A. Lymphocytosis and anemia with many reactive lymphocytes
B. Lymphocytosis without anemia and many reactive lymphocytes
C. Monocytosis and anemia with many atypical monocytes
D. Monocytosis without anemia and many atypical monocytes
L.O. 10.9
3. Opsonization of foreign bodies is defined as:
A. Preparing a foreign body for phagocytosis
B. Degranulation of neutrophils
C. Fusion of cytoplasmic granules
D. Bacteriocidal activity
L.O. 10.4
4. A patient who presents with a low white cell count, thrombocytopenia, elevated liver enzymes, and mulberry-like inclusions in the granulocytes is most likely suffering from:
A. May-Hegglin anomaly
B. Chediak-Higashi anomaly
C. Human ehrlichiosis
D. Alder’s anomaly
L.O. 10.6
5. All of the following are mechanisms by which neutropenia is usually produced except:
A. Decreased production by the bone marrow
B. Impaired release from the bone marrow to the blood
C. Increased destruction
D. Bacterial infection
L.O. 10.12
6. Which of the following statements is common to most lipid storage diseases?
A. They are caused by an amino acid substitution.
B. They are caused by a DNA synthetic defect.
C. They are caused by a missing metabolic enzyme.
D. They are caused by the invasion of a rickettsial organism.
L.O. 10.11
7. An autosomal disorder that manifests itself with large lysosomal inclusions, recurring infections, and albinism is:
A. Chediak-Higashi
B. Pelger-Huët
C. May-Hegglin
D. Alder-Reilly
L.O. 10.5
8. Which of the following is an unusual complication that may occur in infectious mononucleosis?
A. Splenic infarctions
B. Dactylitis
C. Hemolytic anemia
D. Giant platelets
L.O. 10.9
9. The best corrective action for a patient who exhibits platelet satellitism on peripheral blood smear is to:
A. Make a duplicate slide and see if this phenomenon disappears
B. Warm the tube of blood
C. Redraw the sample in sodium citrate
D. Vortex the sample of blood
L.O. N/A
10. A patient who has a persist leukocytosis, Döhle bodies, and an elevated LAP score most likely has a(n):
A. Leukemoid reaction
B. Pelger-Huët anomaly
C. Parasitic infection
D. HIV infection
L.O. 10.3
11. Toxic vacuolization occurs most frequently in:
A. Neutrophils
B. Monocytes
C. Lymphocytes
D. Erythrocytes
L.O. 10.6
12. Toxic granulation in neutrophils is a direct result of:
A. Cytokine production
B. Enhanced lysosome enzyme production
C. Toxic granulation
D. Ehrlichia infection
L.O. 10.6
13. Pelger-Huët anomaly is characterized mainly by:
A. Neutrophils with gray-green granules
B. Lipid depositions in the cytoplasm
C. Giant platelets
D. Hyposegmentation of the nucleus in the neutrophils
L.O. 10.7
14. Döhle bodies consist of:
A. DNA
B. Primary granules
C. Ribosomes RNA
D. Lipid deposits
L.O. 10.6
15. In which white blood cell disorder will you see prominent deposition of granules in every cell line?
A. May-Hegglin anomaly
B. Alder’s anomaly
C. Pelger-Huët anomaly
D. Chediak-Higashi syndrome
L.O. 10.5
16. In which white blood cell disorder will you see gray-green cytoplasmic granules in the neutrophils?
A. May-Hegglin anomaly
B. Alder’s anomaly
C. Pelger-Huët anomaly
D. Chediak-Higashi syndrome
L.O. 10.5
17. HIV inverses the normal ratio of CD4 to CD8 lymphocytes, which is:
A. 1:2
B. 1:1
C. 2:1
D. 4:1
L.O. 10.10
18. All of the following are lipid storage syndromes/diseases except:
A. Gaucher’s disease
B. Tay-Sachs disease
C. Chediak-Higashi syndrome
D. Niemann-Pick disease
L.O. 10.11
True/False
19. Infectious mononucleosis is caused by the EBV virus, which infects B lymphocytes.
L.O. 10.9
20. A patient with bacteremia will have an increase in lymphocytes.
L.O. 10.8 & 10.12
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Test Bank | Hematology in Practice 3e by Betty Ciesla
By Betty Ciesla