Test Bank Chapter 9 Leukopoiesis and Leukopoietic Function

Chapter 9. Leukopoiesis and Leukopoietic Function

Multiple Choice

1. Lymphocyte concentrations in peripheral blood are greatest during what age interval?

A. Immediately after birth

B. Older adult (40 to 70 years)

C. Young adult (16 to 40 years)

D. Young child (1 to 4 years)

L.O. 9.1

2. The “marginating pool” of neutrophils is located:

A. In the kidneys

B. In the tissue

C. Next to marrow sinuses

D. On the blood vessel walls

L.O. 9.1

3. The CBC results for a 3-month-old child are as follows:

WBC 9.5 × 10⁹/L Differential

RBC 3.4 × 10¹²/L Segmented neutrophils 25%

Hgb 6.7 g/dL Lymphocytes 75%

Hct 25%

The absolute lymphocyte count in this patient would be:

A. 1.2 × 10⁹/L

B. 2.4 × 10^9/L

C. 7.1 × 10⁹/L

D. 7.5 × 10⁹/L

L.O. 9.7

4. Which of the following CD markers are more appropriately associated with the myelocyte?

A. CD4, CD8

B. CD33, CD13, CD14

C. CD45, CD33, CD13

D. CD19, CD22

L.O. 9.4

5. One of the primary glands responsible for lymphocyte origination in the infant is the:

A. Thymus

B. Adrenal

C. Thyroid

D. Pituitary

L.O. 9.1 & 9.8

6. An adult has a total white blood cell count of 4.0 × 10⁹/L. The differential count is as follows:

Segmented neutrophils 25%

Lymphocytes 65%

Bands 5%

Monocytes 5%

If the normal values for absolute lymphocyte count are 1.2 to 3.4 × 10⁹/L, which of the following is true?

A. The absolute number of lymphocytes is low.

B. There is an absolute lymphocytosis.

C. There is a relative lymphocytosis.

D. There is an absolute and a relative lymphocytosis.

L.O. 9.7

7. The initial appearance of specific granulation in the granulocytic series is predominantly seen in the:

A. Promyelocyte

B. Metamyelocyte

C. Myelocyte

D. Eosinophil

L.O. 9.3

8. The amount of time a granulocyte spends in the circulation before migrating into the tissues is normally:

A. 8 hours

B. 48 hours

C. 5 days

D. 20 days

L.O. 9.2

9. Monocytes recognize foreign antigens and present them to which of the following cells?

A. B cells

B. T cells

C. Neutrophils

D. NK cells

L.O. 9.9

10. All of the following are features of the lymphatic system except:

A. Stimulation of the kidney by EPO

B. Blood filtration

C. Antibody generation

D. Lymphopoiesis

L.O. 9.8

11. There are ___ maturation stages in the neutrophil.

A. five

B. four

C. three

D. six

L.O. 9.2

12. The N:C ratio in a myeloblast is:

A. 2:1

B. 4:1

C. 3:1

D. 5:1

L.O. 9.1

NARRBEGIN:

NARREND

13. Identify the white cell in this picture.

A. Lymphocyte

B. Myeloblast

C. Promyelocyte

D. Monocyte

NAR: Figure 9-1

L.O. 9.2

NARRBEGIN:

NARREND

14. Identify the white cell in this picture.

A. Band neutrophil

B. Metamyelocyte

C. Promyelocyte

D. Monocyte

NAR: Figure 9-4

L.O. 9.2

NARRBEGIN:

NARREND

15. Identify the white cell in the center of this picture.

A. Band neutrophil

B. Metamyelocyte

C. Promyelocyte

D. Monocyte

NAR: Figure 9-5

L.O. 9.2

16. The plasma cell is responsible for:

A. Humoral immunity

B. Cell-mediated immunity

C. Tumor suppression

D. Delayed hypersensitivity

L.O. 9.9

17. At present, most lymphocyte subpopulations are recognized by their CD markers.

CD refers to:

A. Codon designation

B. Cluster designation

C. Cytoplasmic designation

D. Cytokine designation

L.O. 9.4

18. The spleen harbors approximately ___ of the white blood cell population

A. one-fourth

B. one-half

C. one-third

D. three-fourths

L.O. 9.1

True/False

19. The absolute WBC count refers to the percentage of a particular cell counted from the 100 WBC differential.

L.O. 9.7

20. The primary function of lymphocytes is immunologic.

L.O. 9.6

21. Mature neutrophils have large, evenly sized, bright orange granules in their cytoplasm.

L.O. 9.5

22. Lymphocyte production differs from myeloid cell production in that there are two major sites of cellular production.

L.O. 9.6

23. The myeloid stem cell produces cell lines that end in the production of granulocytes, monocytes, platelets, and red blood cells.

L.O. 9.6

24. NK cells are unique in that they contribute to immunity without the needed aid of T or B cells.

L.O. 9.9

25. It is possible for a patient to have a relatively high lymphocyte count, but with a low white blood cell count, the absolute lymphocyte count may be normal.

L.O. 9.7