Verified Test Bank Human Genetics And Variation Chapter.14 - How Humans Evolved 8e | Test Bank by Robert Boyd by Robert Boyd. DOCX document preview.

Verified Test Bank Human Genetics And Variation Chapter.14

CHAPTER 14: Human Genetics and Variation

MULTIPLE CHOICE

1. Variation refers to ________ between individuals or populations of individuals.

a.

differences

c.

only environmental differences

b.

only genetic differences

d.

only cultural differences

a.

genetic and cultural

c.

genetic and environmental

b.

cultural and environmental

d.

cultural and phenotypic

OBJ: B. Explain why variation in traits influenced by single genes is different from variation in traits affected by many genes. MSC: Understanding

3. Environmental variation refers to

a.

differences between individuals caused by environmental factors.

b.

traits that are caused by the environment, not by genes.

c.

traits that are caused by genes, not by the environment.

d.

variation in the environment over time caused by climate change.

a.

differences between individuals caused by the genes they inherit.

b.

traits that are caused by the environment, not by genes.

c.

traits that are caused by genes, not by the environment.

d.

mutations that cause novel genes to arise.

OBJ: B. Explain why variation in traits influenced by single genes is different from variation in traits affected by many genes. MSC: Remembering

5. Different human groups

a.

have the same potential for the known genetic diseases.

b.

all have the same potential for most diseases, but for some groups the disease is environmental; for others, it is genetic.

c.

vary in the incidence of many genetically transmitted diseases.

d.

have similar genetic diseases but vary in how the diseases are accepted culturally.

a.

are determined by genes more than by environment.

b.

cannot be influenced by cultural practices.

c.

can be influenced by genes, environment, and culture.

d.

are entirely environmental.

OBJ: B. Explain why variation in traits influenced by single genes is different from variation in traits affected by many genes. MSC: Understanding

7. Which of the following is/are example(s) of variation among groups?

a.

the distribution of Tay-Sachs among Jewish populations

b.

differences in body weight between parents and their offspring

c.

variation in height for college basketball players

d.

variation in height and weight for jockeys

a.

genes.

c.

environment and culture.

b.

genes and environments.

d.

genes, environments, and culture.

OBJ: B. Explain why variation in traits influenced by single genes is different from variation in traits affected by many genes. MSC: Understanding

9. Environmental variation includes factors such as differences in

a.

height.

c.

genes.

b.

weight.

d.

climate.

a.

It is caused by a lack of protein.

b.

It is caused by a lack of iron.

c.

It causes unusually shaped red blood cells.

d.

It causes unusually shaped blood vessels.

OBJ: B. Explain why variation in traits influenced by single genes is different from variation in traits affected by many genes. MSC: Remembering

11. Evidence that a trait is caused by a single gene includes

a.

inheritance of Tay-Sachs disease in certain Jewish populations.

b.

Hardy–Weinberg equilibrium.

c.

observing a pattern of inheritance of dominant genes.

d.

observing Mendelian inheritance patterns.

a.

0%

c.

50%

b.

75%

d.

100%

OBJ: D. Explain how genetic drift and natural selection create variation among populations in traits influenced by single genes. MSC: Applying

13. Which of the following statements about the FOXP2 gene is correct?

a.

It causes a heritable disease called PKU.

b.

It changed in humans because of directional selection.

c.

It is an example of environmental variation.

d.

It is expressed in the tongue during prenatal development.

a.

10,000

c.

200,000

b.

500,000

d.

75,000

OBJ: D. Explain how genetic drift and natural selection create variation among populations in traits influenced by single genes. MSC: Remembering

15. Tay-Sachs disease may give partial resistance to tuberculosis

a.

in adults who are homozygous.

b.

and may be an example of a balanced polymorphism.

c.

and is absent in Jews of Eastern European ancestry, causing them to be more susceptible to the disease.

d.

but increases susceptibility to malaria.

a.

100%

c.

35%

b.

50%

d.

15%

OBJ: C. Describe how mutation and natural selection maintain differences at single genetic loci between people in the same population. MSC: Remembering

17. The evolution of lactase persistence in Africa and Europe was the result of

a.

convergent evolution.

b.

drift acting on isolated populations.

c.

gene flow between Africans and Europeans.

d.

the retention of an ancestral trait.

a.

analyses of their pottery show residues of compounds found only in milk.

b.

isotopic analysis of people’s teeth shows they drank milk.

c.

the amount of genetic diversity for milk proteins in domesticated cattle indicates that people kept small herds.

d.

the amount of genetic diversity in domesticated cattle is greatest in southeastern Europe.

OBJ: C. Describe how mutation and natural selection maintain differences at single genetic loci between people in the same population. MSC: Understanding

19. Which of the following statements correctly describes non-insulin-dependent diabetes?

a.

It was a seriously deleterious trait in the past and therefore no longer exists.

b.

It causes blood-sugar levels to rise above normal because the cells of the body do not respond properly to hemoglobin.

c.

It has no known genetic basis.

d.

It is caused by the same genetic mutation that causes sickle-cell disease.

a.

trait that conferred a benefit in the past but is no longer beneficial.

b.

trait that was maladaptive in the past but now confers a significant benefit.

c.

genetic trait that can be beneficial or not depending on the presence or absence of malaria parasites.

d.

environmentally caused disease that has a genetically based cure.

OBJ: D. Explain how genetic drift and natural selection create variation among populations in traits influenced by single genes. MSC: Remembering

21. Selection can maintain variation within populations if heterozygotes

a.

are excluded from the population by environmental factors.

b.

are increased in number by fixation.

c.

mutate into homozygotes at the same rate as they form.

d.

have higher fitness than either of the two homozygotes for a given gene.

a.

porphyria variegata.

c.

lactose tolerance.

b.

non-insulin-dependent diabetes.

d.

cystic fibrosis.

OBJ: D. Explain how genetic drift and natural selection create variation among populations in traits influenced by single genes. MSC: Remembering

23. A selection–mutation balance occurs when

a.

mutation introduces alleles that selection favors for one reason, even if the alleles also cause a trait that is deleterious.

b.

mutation introduces deleterious recessive alleles at a rate that is similar to or higher than the rate at which selection removes the alleles.

c.

a large number of deleterious mutations occur over a short period of time, and there is no subsequent selection against them.

d.

a beneficial mutation arises and spreads for a specific period of time, then the mutation becomes deleterious in a new environment and is removed by selection over a similar period of time.

a.

balance between mutation and selection.

b.

balance between selection and drift.

c.

state in which two alleles remain in a population because of heterozygote advantage.

d.

state in which environmental and genetic causes of a trait (a “morph”) are roughly equal.

OBJ: C. Describe how mutation and natural selection maintain differences at single genetic loci between people in the same population. MSC: Applying

25. Deleterious alleles can remain at low frequencies in populations because

a.

mutation can alter the allele to decrease its lethality.

b.

most individuals who carry the gene are heterozygous and do not suffer consequences of having two copies of the gene.

c.

heterozygotes most often pass on the dominant allele.

d.

many, but not all, homozygous-recessive individuals die.

a.

0.10

c.

0.001

b.

0.01

d.

0.0001

OBJ: D. Explain how genetic drift and natural selection create variation among populations in traits influenced by single genes. MSC: Applying

27. Variation among groups at a single locus can be maintained by

a.

different environments.

c.

single nucleotide polymorphisms.

b.

haplotypes.

d.

recombination.

a.

haplotypes.

c.

founder effect.

b.

recombination.

d.

single nucleotide polymorphisms.

OBJ: C. Describe how mutation and natural selection maintain differences at single genetic loci between people in the same population. MSC: Understanding

29. Lactase persistence is controlled by

a.

variation at a single locus.

c.

factors not related to genetics.

b.

variation at many loci.

d.

a selective haplotype.

a.

where pastoralism is common.

c.

where malaria is common.

b.

where drift has been strong.

d.

where hemoglobin is rare.

OBJ: C. Describe how mutation and natural selection maintain differences at single genetic loci between people in the same population. MSC: Understanding

31. Variation may exist because environments have recently changed and genes that were previously beneficial have not yet been eliminated. This may describe

a.

Tay-Sachs disease.

c.

non-insulin-dependent diabetes.

b.

sickle-cell anemia.

d.

P. falciparum malaria.

a.

long haplotypes

c.

candidate genes

b.

instances of founder effect

d.

balanced polymorphisms

OBJ: D. Explain how genetic drift and natural selection create variation among populations in traits influenced by single genes. MSC: Understanding

33. A new beneficial mutation causes a(n) ________ in which both the mutation and the DNA linked to the mutation on the same chromosome spread throughout the population.

a.

environmental covariation

c.

selective sweep

b.

specific language impairment

d.

situation of negative selection

a.

hair texture.

b.

morphology of the skull.

c.

the immune system and affect human responses to viruses.

d.

digestion and affect the metabolism of alcohol, carbohydrates, and fatty acids.

OBJ: D. Explain how genetic drift and natural selection create variation among populations in traits influenced by single genes. MSC: Remembering

35. ________ tends to blur the effects of population expansions.

a.

Mutation

c.

Gene flow

b.

Genetic drift

d.

Founder effect

a.

percentage of a trait determined by environment.

b.

proportion of observed variation due to genetic variation.

c.

extent to which genetic control of a trait is under the influence of selection.

d.

measure of how well genotype matches phenotype.

OBJ: E. Describe how to measure genetic variation in complex traits.

MSC: Understanding

37. Environmental covariation refers to the

a.

difference between genetic and environmental variation.

b.

similarity between parents and offspring.

c.

similarity between the environments of parents and offspring.

d.

difference between parents and offspring.

a.

twins derived from two zygotes.

b.

twins derived from a single zygote.

c.

twins whose degree of relatedness is 0.5.

d.

also known as “fraternal twins.”

OBJ: D. Explain how genetic drift and natural selection create variation among populations in traits influenced by single genes. MSC: Remembering

39. If variation in a trait is largely due to variation in genes, then

a.

monozygotic twins should be more similar to each other than dizygotic twins.

b.

dizygotic twins should be more similar to each other than monozygotic twins.

c.

monozygotic and dizygotic twins should be equally similar to one another.

d.

dizygotic twins will be exactly alike.

a.

twin studies.

c.

mutation–selection balance.

b.

heterozygote advantage.

d.

selection.

OBJ: D. Explain how genetic drift and natural selection create variation among populations in traits influenced by single genes. MSC: Understanding

41. Variation in height is heritable within groups. Therefore, ________ height differences among groups.

a.

genetic differences cause

b.

environmental differences cause

c.

cultural differences cause

d.

genetic, environmental, or cultural differences may be responsible for

a.

the fetal environments of monozygotic and dizygotic twins are equally similar.

b.

the early postnatal environments of monozygotic and dizygotic twins diverge quickly.

c.

monozygotic twins share fewer genes.

d.

dizygotic twins are essentially the same as nontwin siblings in both genetic and environmental factors.

OBJ: F. Assess why the existence of genetic variation within populations in complex traits does not imply that there is variation among populations. MSC: Understanding

43. Classifying humans into races is not possible because

a.

genetic variation is continuous.

b.

the placement of individuals within any single category is clear and obvious.

c.

classifications based on different characters lead to consistent groupings.

d.

race is not culturally relevant.

a.

three races: Caucasian, African, and Asian.

b.

five races: Caucasian, African, Asian, American Indian, and indigenous Australian.

c.

seven races: Caucasian, African, Asian, American Indian, Australian, Polynesian, and Oceanic.

d.

one race: human.

OBJ: G. Evaluate the argument that folk concepts of race do not correspond to any meaningful biological category. MSC: Understanding

45. Most genetic variation exists

a.

within local groups.

c.

between races.

b.

among local groups within races.

d.

between local groups.

a.

meaningful biological concept.

b.

biological reality only when the distribution of many genetic traits is considered.

c.

culturally constructed category.

d.

important tool for understanding human variation.

OBJ: F. Assess why the existence of genetic variation within populations in complex traits does not imply that there is variation among populations. MSC: Understanding

47. Genetic variation within local groups reflects about ________ of the genetic variation in the human species.

a.

5%

c.

85%

b.

35%

d.

95%

a.

selection for taller people, who do better in the modern world.

b.

more extensive exercise in professional gyms.

c.

an increase in available food and decrease in disease.

d.

walking and running being replaced by driving.

OBJ: F. Assess why the existence of genetic variation within populations in complex traits does not imply that there is variation among populations. MSC: Understanding

49. Which of the following statements about race is true?

a.

The human species can be naturally divided into a small number of distinct races.

b.

Members of different races are different in important ways, so that knowing a person’s race gives you important information about what he or she is like.

c.

Members of each race are genetically similar to each other and genetically different from members of other races.

d.

We cannot determine a discrete number of racial categories.

a.

is based on stature rather than skin color.

b.

uses “color,” but the term only refers to hair color.

c.

is based on a presumption of ancestry that has been shown to be incorrect.

d.

reflects genetic ancestry accurately, but is still unfair.

OBJ: G. Evaluate the argument that folk concepts of race do not correspond to any meaningful biological category. MSC: Understanding

51. Genetic results for so-called black and white Brazilians reveals

a.

that racial categories are consistent with genetic data.

b.

little correlation between phenotype and ancestry.

c.

that, although Brazilians can be categorized into race based on phenotype, they cannot be categorized genetically.

d.

that folk classifications are genetically meaningful.

a.

1.0%

c.

3.0%

b.

2.5%

d.

0.75%

OBJ: A. Describe how humans differ genetically from other apes.

MSC: Remembering

53. ________ do not produce any change in the amino acid sequence of a protein.

a.

Transposable elements

c.

Microsatellite loci

b.

Synonymous substitutions

d.

Highly accelerated regions

a.

is related to the rapid evolution of the large and complex human brain.

b.

has a slower rate of change in humans than in other lineages.

c.

is found in a coding region and results in new proteins.

d.

is involved in speech production along with FOXP2.

OBJ: A. Describe how humans differ genetically from other apes.

MSC: Remembering

55. What percentage of protein-coding genes of humans and chimpanzees differ in a way that produces different proteins?

a.

10%

c.

50%

b.

30%

d.

70%

a.

fewer nonsynonymous substitutions than synonymous substitutions

b.

more nonsynonymous substitutions than synonymous substitutions

c.

no difference in nonsynonymous and synonymous substitutions

d.

There is too little information to answer this question.

OBJ: A. Describe how humans differ genetically from other apes.

MSC: Understanding

57. The rates of change in the human lineage for highly accelerated regions of the genome that have undergone negative selection imply that they have been shaped by

a.

genetic drift.

c.

mutation.

b.

natural selection.

d.

sexual selection.

DIF: Moderate REF: Explaining Genetic Variation

OBJ: E. Describe how to measure genetic variation in complex traits.

MSC: Understanding

2. Why are there many deleterious, often fatal, recessive alleles found at low frequencies in human populations?

DIF: Moderate REF: Variation in Traits Influenced by Single Genes

OBJ: C. Describe how mutation and natural selection maintain differences at single genetic loci between people in the same population. MSC: Understanding

3. Why is the hemoglobin S allele found in very high frequencies in some populations even though it is a lethal recessive?

DIF: Easy REF: Variation in Traits Influenced by Single Genes

OBJ: C. Describe how mutation and natural selection maintain differences at single genetic loci between people in the same population. MSC: Understanding

4. Describe and contrast selection and genetic drift as two major causes of genetic variation among human groups.

DIF: Moderate REF: Variation in Traits Influenced by Single Genes

OBJ: D. Explain how genetic drift and natural selection create variation among populations in traits influenced by single genes. MSC: Understanding

5. Why is there variation between human populations in the ability to digest lactose? How has natural selection affected and maintained this variation?

DIF: Moderate REF: Variation in Traits Influenced by Single Genes

OBJ: D. Explain how genetic drift and natural selection create variation among populations in traits influenced by single genes. MSC: Understanding

6. You have sampled height from two populations: the Maasai of East Africa and the Inuits of Alaska. You have determined that there is a significant difference in height between these two populations, with Inuits being of shorter height than the Maasai. Can you argue that this variation that you observe due solely to genetics? Why or why not? How would you test the hypothesis that stature in each of these two groups is genetic?

DIF: Difficult REF: Variation in Traits Influenced by Single Genes

OBJ: F. Assess why the existence of genetic variation within populations in complex traits does not imply that there is variation among populations. MSC: Applying

7. Explain the rationale for, and assumptions of, using twins to estimate heritability.

DIF: Moderate REF: Variation in Traits Influenced by Single Genes

OBJ: F. Assess why the existence of genetic variation within populations in complex traits does not imply that there is variation among populations. MSC: Understanding

8. Why do scientists no longer believe that race is a meaningful biological concept?

DIF: Moderate REF: The Race Concept

OBJ: G. Evaluate the argument that folk concepts of race do not correspond to any meaningful biological category. MSC: Understanding

9. Explain the changes in the structural or protein-coding genes of humans and chimpanzees.

DIF: Moderate REF: How Humans Are Different from Other Apes

OBJ: A. Describe how humans differ genetically from other apes.

MSC: Understanding

10. How are modern humans genetically different from the chimpanzee?

DIF: Moderate REF: How Humans Are Different from Other Apes

OBJ: A. Describe how humans differ genetically from other apes.

MSC: Understanding

11. Although only a small fraction of protein-coding genes shows evidence of selection since the divergence of human and chimpanzee lineages, humans and chimpanzees are vastly different in their phenotypes. How can this be?

DIF: Moderate REF: How Humans Are Different from Other Apes

OBJ: A. Describe how humans differ genetically from other apes.

MSC: Applying

Document Information

Document Type:
DOCX
Chapter Number:
14
Created Date:
Aug 21, 2025
Chapter Name:
Chapter 14 Human Genetics And Variation
Author:
Robert Boyd

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