Consolidating Ltp Translation And Ch.5 Complete Test Bank 3e - Neurobiology Learning 3e | Test Bank Rudy by Jerry W. Rudy. DOCX document preview.

Consolidating Ltp Translation And Ch.5 Complete Test Bank 3e

Chapter 5: Consolidating LTP: Translation and Transcription

Test Bank

Type: true-false

Title: Chapter 5 - Question 1

1. According to the de novo protein synthesis (DNPS) hypothesis, long-lasting memories require that the learning experience generate new proteins.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 2

2. The consolidating event is likely the building of an enlarged, stable actin cytoskeleton.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 3

3. Anisomycin causes LTP produced by intense, high-frequency stimulation to resemble LPT produced by a weak-induction stimulus.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 4

4. The fact that anisomycin has no effect on short-lasting LTP implies that it requires new protein to be generated.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 5

5. Transcription refers to the creation of new protein.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 6

6. Both transcription and translation depend on post-translation modifications of existing protein.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 7

7. Local protein synthesis depends on already existing mRNA.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 8

8. CREB is an important translation factor found in dendrites.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 9

9. To produce mRNA, signaling molecules enter the nucleus to phosphorylate transcription factors.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 10

10. Dendritic protein synthesis (local protein synthesis) is not sufficient to produce relatively long-lasting LTP.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 11

11. Genomic signaling refers to processes initiated by synaptic events that lead to the transcription of new mRNA.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 12

12. Synapse-to-nucleus signaling depends on voltage-gated calcium channels, but soma-to-nucleus signaling does not.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 13

13. The first of the two waves of protein synthesis depends on genomic signaling.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 14

14. Extracellular calcium is derived from the endoplasmic reticulum.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 15

15. NMDA receptors and voltage-gated calcium channels allow extracellular calcium to enter the neuron.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 16

16. Calcium-induced calcium release refers to extracellular calcium entering the cell.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 17

17. Calcium-induced calcium release occurs when calcium entering via NMDA receptors binds to RyRs on the endoplasmic reticulum.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 18

18. If the IP3 receptor is antagonized, a short lasting LTP1 can still be produced.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 19

19. Metabotropic glutamate receptors have ion channels.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 20

20. Antidromic stimulation can convert a short-lasting LTP produced by a weak induction into a long-lasting LTP.

a. True

b. False

Type: true-false

Title: Chapter 5 - Question 21

21. In the soma-to-nucleus cascade, repetitive action potentials are assumed to open voltage-dependent calcium channels.

a. True

b. False

Type: essay/short answer question

Title: Chapter 5 - Question 22

22. What two general processes are necessary for memory consolidation?

Type: essay/short answer question

Title: Chapter 5 - Question 23

23. Describe the de novo protein synthesis hypothesis.

Type: essay/short answer question

Title: Chapter 5 - Question 24

24. Why has anisomycin been used to study LTP?

Type: essay/short answer question

Title: Chapter 5 - Question 25

25. Describe the influence of the protein synthesis inhibitor anisomycin on LTP.

Type: essay/short answer question

Title: Chapter 5 - Question 26

26. A strong stimulus initiates what two rounds of protein synthesis?

Type: essay/short answer question

Title: Chapter 5 - Question 27

27. Where is mRNA found in the neuron?

Type: essay/short answer question

Title: Chapter 5 - Question 28

28. Why does separating the dendrites from the soma provide evidence for local protein synthesis?

Type: essay/short answer question

Title: Chapter 5 - Question 29

29. Why is emetine important?

Type: essay/short answer question

Title: Chapter 5 - Question 30

30. What two major findings illustrate the important role local protein synthesis plays in L-LTP?

Type: essay/short answer question

Title: Chapter 5 - Question 31

31. What is a major feature of the genomic signaling hypothesis?

Type: essay/short answer question

Title: Chapter 5 - Question 32

32. What are plasticity products (PPs)?

Type: essay/short answer question

Title: Chapter 5 - Question 33

33. Describe the order of events in the synapse-to-nucleus signaling model.

Type: essay/short answer question

Title: Chapter 5 - Question 34

34. What is the major assumption in the soma-to-nucleus signaling model?

Type: essay/short answer question

Title: Chapter 5 - Question 35

35. Provide experimental support for the soma-to-nucleus model.

Type: essay/short answer question

Title: Chapter 5 - Question 36

36. Give two reasons why the ER is important in the context of synaptic plasticity.

Type: essay/short answer question

Title: Chapter 5 - Question 37

37. What are the calcium sources important for LTP?

Type: essay/short answer question

Title: Chapter 5 - Question 38

38. What were the results when the protein synthesis inhibitor emetine was applied to the entire hippocampal slice and when it was applied to only the soma?

Type: essay/short answer question

Title: Chapter 5 - Question 39

39. What is calcium-induced calcium release (CICR)?

Type: essay/short answer question

Title: Chapter 5 - Question 40

40. Name the two receptors that can release calcium from the ER into the dendritic compartment. What do they bind to?

Type: essay/short answer question

Title: Chapter 5 - Question 41

41. Activating four sources can increase calcium levels. What are these sources?

Type: essay/short answer question

Title: Chapter 5 - Question 42

42. Why is the activation of CREB a post-translation modification?

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Document Type:
DOCX
Chapter Number:
5
Created Date:
Aug 21, 2025
Chapter Name:
Chapter 5 Consolidating Ltp Translation And Transcription
Author:
Jerry W. Rudy

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