Test Bank Docx Ch.4 Stabilizing Long-Term Potentiation 3e - Neurobiology Learning 3e | Test Bank Rudy by Jerry W. Rudy. DOCX document preview.
Chapter 4: Stabilizing Long-Term Potentiation
Test Bank
Type: true-false
Title: Chapter 4 - Question 1
1. Application of a low-frequency stimulus within a day after the TBS-inducing stimulus is sufficient to interrupt the development of a long-lasting LTP.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 2
2. Low-frequency stimulation delivered 15 minutes after LTP induction has no effect on stabilization
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 3
3. When cofilin is phosphorylated, F-actin is more likely to remain in its filament state.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 4
4. Applying drugs that inhibit myosin IIb prior to TBS prevents the induction and stabilization of LTP.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 5
5. When cofilin is phosphorylated actin polymerization is prevented.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 6
6. Neural cadherins can exist as either monomers or cis-stranded dimers, with equal adhesive properties.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 7
7. Neutralizing the response of β integrins to extracellular ligands prevents enduring LTP normally produced by TBS, but it has no effect on the initial induction of LTP.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 8
8. Large spines endure longer than small spines.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 9
9. When cofilin is phosphorylated actin polymerization is prevented.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 10
10. Drugs like latrunculin and cytochalasin prevent actin polymerization.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 11
11. In it nonactive state CaMKII bundles active filament.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 12
12. In its non-phosphorylated state cofilin can sever actin filaments.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 13
13. When actin polymerization is inhibited the actin cytoskeleton will enlarge.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 14
14. Inhibiting NMDA receptors will prevent spine enlargement.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 15
15. Stabilization of LTP depends on the regulation of actin dynamics.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 16
16. The generation but not the stabilization of LTP depends on the reorganization of N-cadherins.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 17
17. The stabilization of LTP depends on the reorganization of N-cadherins, but the generation of it does not.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 18
18. Applying latrunculin and cytochalasin to the LTP slice 15 minutes following induction has no effect on LTP stabilization.
a. True
b. False
Type: true-false
Title: Chapter 4 - Question 19
19. The delivery of low-frequency stimulation prior to induction of LTP has no effect on its generation but prevents LTP stabilization.
a. True
b. False
Type: essay/short answer question
Title: Chapter 4 - Question 20
20. Explain the observation that people with amnesia resulting from an accident often can recall events that took place long ago but not events that occurred within minutes of the accident?
Type: essay/short answer question
Title: Chapter 4 - Question 21
21. How can a weak stimulus (low frequency) be used to prevent the development of a long-lasting LTP?
Type: essay/short answer question
Title: Chapter 4 - Question 22
22. What is a benefit of larger spines?
Type: essay/short answer question
Title: Chapter 4 - Question 23
23. Identify a role for inactive CaMKII.
Type: essay/short answer question
Title: Chapter 4 - Question 24
24. Why is non-phosphorylated cofilin important to the subsequent enlargement of the spine?
Type: essay/short answer question
Title: Chapter 4 - Question 25
25. What is the role of LIMK in the stabilization of LTP?
Type: essay/short answer question
Title: Chapter 4 - Question 26
26. In Harou Kasai’s study of single spine enlargement, what was the effect of antagonizing NMDA receptors?
Type: essay/short answer question
Title: Chapter 4 - Question 27
27. In Harou Kasai’s study of single spine enlargement, what was the effect of the actin polymerization inhibitor, latrunculin
Type: essay/short answer question
Title: Chapter 4 - Question 28
28. The severing properties of cofilin are initially important to stabilization. However, it is important that this function be terminated. How does this normally happen?
Type: essay/short answer question
Title: Chapter 4 - Question 29
29. The severing properties of cofilin are initially important to stabilization. However, it is important this this function be terminated. Why?
Type: essay/short answer question
Title: Chapter 4 - Question 30
30. Describe how actin filaments are broken down into smaller units. Why is this beneficial?
Type: essay/short answer question
Title: Chapter 4 - Question 31
31. What is an “adhesive zipper”?
Type: essay/short answer question
Title: Chapter 4 - Question 32
32. Briefly describe how the delivery of low-frequency stimulation prior to induction of LTP affects its generation and its stabilization.
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