Exam Questions Chapter.3 Generating Long-Term Potentiation - Neurobiology Learning 3e | Test Bank Rudy by Jerry W. Rudy. DOCX document preview.
Chapter 3: Generating Long-Term Potentiation
Test Bank
Type: true-false
Title: Chapter 3 - Question 1
1. Glutamate is an excitatory neurotransmitter.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 2
2. Glutamate receptors involved in LTP are found along the axon.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 3
3. Calcium is a second messenger.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 4
4. Second messengers can be quickly synthesized.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 5
5. Phosphatases add phosphates to other proteins.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 6
6. Ionotropic receptors protrude outside and inside the cell.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 7
7. Competitive antagonists, such as APV, can replace a ligand and cause conformational changes in the receptor.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 8
8. AMPA receptors influx mainly Na+; NMDA receptors influx both Na+ and Ca2+.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 9
9. The opening of NMDA receptor channels require synaptic depolarization.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 10
10. Antagonizing NMDA receptor after LTP is established prevents LTP expression.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 11
11. Constitutive AMPA receptor trafficking is primarily a diffusion process.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 12
12. Stargazin is critical to the opening of the AMPA receptor.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 13
13. Stargazin is critical to the trapping of AMPA receptors in the PSD.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 14
14. PSD-95 is critical to the trapping of AMPA receptors in the PSD.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 15
15. The delivery of AMPA receptors produced by LTP induction involves both lateral diffusion and the exocytic processes.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 16
16. CaMKII is important in the delivery of AMPA receptors to the PSD because it phosphorylates stargazin.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 17
17. The degradation of the actin cytoskeleton depends on spectrins degrading calpains.
a. True
b. False
Type: true-false
Title: Chapter 3 - Question 18
18. NMDA receptors but not AMPA receptors influx calcium.
a. True
b. False
Type: essay/short answer question
Title: Chapter 3 - Question 19
19. What is an excitatory synapse?
Type: essay/short answer question
Title: Chapter 3 - Question 20
20. What is APV, and what is its function?
Type: essay/short answer question
Title: Chapter 3 - Question 21
21. What were Collingridge’s results that established the importance of NMDA receptors to our understanding of LTP?
Type: essay/short answer question
Title: Chapter 3 - Question 22
22. What are the two conditions that must be met for Ca2+ ions to flow into the neuron?
Type: essay/short answer question
Title: Chapter 3 - Question 23
23. Why would an increase in the population of AMPA receptors increase the fEPSP?
Type: essay/short answer question
Title: Chapter 3 - Question 24
24. Why is the NMDA receptor an ionotropic glutamate receptor?
Type: essay/short answer question
Title: Chapter 3 - Question 25
25. What is the role of calpain in the generation of LTP?
Type: essay/short answer question
Title: Chapter 3 - Question 26
26. Why should inhibiting NMDA receptors prevent the degradation of the actin cytoskeleton?
Type: essay/short answer question
Title: Chapter 3 - Question 27
27. Why should inhibiting AMPA receptors prevent the generation of LTP?
Type: essay/short answer question
Title: Chapter 3 - Question 28
28. Why should inhibiting AMPA receptors prevent the expression of LTP?