Blood Test Bank Docx Ch12 - Hole’s Anatomy and Physiology 13e Complete Test Bank by David Shier. DOCX document preview.

Blood Test Bank Docx Ch12

Chapter 12

Blood

 


Multiple Choice Questions
 

1.

The percentage of red blood cells in a sample of human blood is normally about  
 

A. 

15%.

B. 

30%.

C. 

45%.

D. 

60%.

E. 

80%.

 

2.

Hematocrit is  
 

A. 

the percent of red blood cells in a blood sample.

B. 

a disease.

C. 

a clotting factor.

D. 

the color of plasma.

E. 

none of the above.

 

3.

The biconcave cells in blood that lack nuclei when they are mature are the  
 

A. 

white blood cells.

B. 

red blood cells.

C. 

platelets.

D. 

macrophages.

E. 

plasma cells.

 

4.

Which of the following elements is included in hemoglobin molecules? 
 

A. 

cobalt

B. 

copper

C. 

iron

D. 

iodine

E. 

calcium

 

5.

The condition called cyanosis is caused by an increased blood concentration of

 
 

A. 

deoxyhemoglobin.

B. 

oxyhemoglobin.

C. 

carbon dioxide.

D. 

carbon monoxide.

E. 

oxygen.

 

6.

Sickle cell disease, in which red blood cells contain abnormal hemoglobin,  is caused by  
 

A. 

a lack of dietary iron.

B. 

a lack of intrinsic factor.

C. 

an excess of hemoglobin.

D. 

a mutation.

E. 

a virus.

 

7.

Which of the following is an agranulocyte? 
 

A. 

basophil

B. 

eosinophil

C. 

monocyte

D. 

neutrophil

E. 

polymorphonuclear leukocyte

 

8.

Which of the following usually accounts for the smallest percentage of leukocytes in a blood sample? 
 

A. 

monocytes

B. 

eosinophils

C. 

basophils

D. 

lymphocytes

E. 

neutrophils

 

9.

The most active phagocytic cells among the leukocytes are 
 

A. 

basophils and eosinophils.

B. 

neutrophils and monocytes.

C. 

lymphocytes and neutrophils.

D. 

monocytes and lymphocytes.

 

10.

A primary function of lymphocytes is to  
 

A. 

phagocytize damaged cells.

B. 

produce enzymes that dissolve blood clots.

C. 

release substances that initiate blood clots.

D. 

act against foreign substances.

E. 

stimulate formation of red blood cells.

 

11.

The normal white blood cell count is between  
 

A. 

400-1,100 cells per microliter of blood.

B. 

4,000-11,000 cells per microliter of blood.

C. 

40,000-110,000 cells per microliter of blood.

D. 

4,000,000-11,000,000 cells per microliter of blood.

E. 

130,000-360,000 cells per microliter of blood.

 

12.

Platelets are best defined as  
 

A. 

giant, multinucleated cells.

B. 

cytoplasmic fragments of cells.

C. 

immature leukocytes.

D. 

lymphoid cells.

E. 

stem cells.

 

13.

Patients with leukemia have a tendency to bleed because they have a deficiency of  
 

A. 

vitamin K.

B. 

red blood cells.

C. 

platelets.

D. 

leukocytes.

E. 

plasma.

 

14.

The most important action of plasma albumins is  
 

A. 

acting as antibodies of immunity.

B. 

helping to control bleeding.

C. 

serving as energy sources.

D. 

helping to maintain blood osmotic pressure.

E. 

transporting lipids and fat-soluble vitamins.

 

15.

Nonprotein nitrogenous substances include  
 

A. 

amino acids.

B. 

urea.

C. 

uric acid.

D. 

creatine.

E. 

all of these.

 

16.

Of the plasma electrolytes, the most abundant are  
 

A. 

sodium and chloride ions.

B. 

sodium and potassium ions.

C. 

potassium and calcium ions.

D. 

phosphate and sulfate ions.

E. 

magnesium and phosphate ions.

 

17.

As a platelet plug forms, platelets release the vasoconstricting substance called  
 

A. 

collagen.

B. 

creatine.

C. 

serotonin.

D. 

fibrin.

E. 

acetylcholine.

 

18.

The basic event in the formation of a blood clot is the change of  
 

A. 

fibrinogen to fibrin.

B. 

fibrin to fibrinogen.

C. 

thrombin to prothrombin.

D. 

vitamin K to prothrombin.

E. 

red blood cells to platelets.

 

19.

Which of the following serves as an enzyme in the blood coagulation mechanism? 
 

A. 

thrombin

B. 

prothrombin

C. 

fibrinogen

D. 

fibrin

E. 

serotonin

 

20.

Which of the following is NOT required in the formation of a blood clot? 
 

A. 

calcium

B. 

fibrinogen

C. 

prothrombin

D. 

albumin

E. 

vitamin K

 

21.

Prothrombin time is a blood test used to evaluate  
 

A. 

ABO blood type.

B. 

Rh blood type.

C. 

blood clotting.

D. 

blood flow.

E. 

serotonin levels.

 

22.

Two substances that are useful for dissolving blood clots are  
 

A. 

thrombus and embolus.

B. 

urokinase and streptokinase.

C. 

factor IV and factor XII.

D. 

calcium ions and prothrombin activator.

E. 

vitamin K and calcium.

 

23.

The red blood cells of type AB blood have on their surfaces  
 

A. 

antigens A and B.

B. 

antigen A only.

C. 

antigen B only.

D. 

neither antigen A nor B.

E. 

different A and B antigens depending upon circumstances.

 

24.

The most common blood type in the United States has which type(s) of antibodies in its plasma? 
 

A. 

anti-A antibodies only

B. 

anti-B antibodies only

C. 

both anti-A and anti-B antibodies

D. 

neither anti-A nor anti-B antibodies

E. 

anti-O antibodies

 

25.

Erythroblastosis fetalis can be prevented by treating 
 

A. 

Rh-positive mother with Rh-positive blood cells.

B. 

Rh-positive mothers with anti-Rh agglutinins (antibodies).

C. 

Rh-negative mothers with Rh-positive blood cells.

D. 

Rh-negative mothers with anti-Rh agglutinins (antibodies).

E. 

Rh-positive fetuses with Rh-positive blood cells.

 

26.

This component normally makes up about 45% of blood volume and this percentage is known as the hematocrit. 
 

A. 

red blood cells

B. 

white blood cells

C. 

plasma

D. 

platelets

 

27.

Which statement about blood, if any, is false? 
 

A. 

Blood is a transport system for nutrients, wastes, hormones and heat distribution.

B. 

Blood can be a transport system for disease.

C. 

Blood connects the body's internal environment to the external environment.

D. 

The formed elements are suspended in the plasma.

E. 

A - d are all true of the blood.

 

28.

Adults of average height and weight have a total blood volume of about ________. 
 

A. 

5 L

B. 

7 L

C. 

4 L

D. 

6 L

 

29.

This structural feature of erythrocytes (RBCs) provides increased surface area for oxygen diffusion. 
 

A. 

microvilli

B. 

biconcave disc shape

C. 

overlapping folds in the plasma membrane

 

30.

The flattened bioconcave disc shape of an erythrocyte __________. 
 

A. 

increases the cell's surface area-to-volume ratio

B. 

allows more hemoglobin molecules to be closer to the plasma membrane

C. 

enhances the cell's ability to divide

D. 

all of these

E. 

both a and b

 

31.

The blueish color of skin and mucous membranes due to prolonged oxygen deficiency is called ________. 
 

A. 

carbon monoxide poisoning

B. 

hypoxia

C. 

cyanosis

D. 

oxyhemoglobin

 

32.

A high red blood cell count can indicate a greater ability to carry oxygen. A normal count for men is about ________ and for women it is about ________. 
 

A. 

4.2 - 4.7 million cells/mm3, 5.4 - 6.1 million cells/mm3

B. 

4.2 - 5.4 million cells/mm3, 4.7 - 6.1 million cells/mm3

C. 

5.4 - 6.1 million cells/mm3, 4.2 - 4.7 million cells/mm3

D. 

4.7 - 6.1 million cells/mm3, 4.2 - 5.4 million cells/mm3

 

33.

Red blood cell formation is called _______ . 
 

A. 

hemostasis

B. 

erythromitosis

C. 

hemoporesis

D. 

erythropoiesis

 

34.

What is the average life span of an erythrocyte? 
 

A. 

6 months

B. 

4 months

C. 

2 years

D. 

5 months

E. 

3 months

 

35.

Formation of red blood cells is stimulated by this hormone. 
 

A. 

aldosterone

B. 

erythropoietin 

C. 

ACTH

D. 

calcitonin

E. 

somatomedin

 

36.

All blood cells and platelets develop from this stem cell. 
 

A. 

megacaryoblast

B. 

myeloblast

C. 

hemocytoblast

D. 

promyelocyte

 

37.

The rate of red blood cell formation is regulated by negative feedback. Considering the function of red blood cells, which one of the following conditions is most likely to cause increased RBC production? 
 

A. 

an over abundance of plasma proteins

B. 

a viral infection accompanied by high fever

C. 

prolonged exposure to cold temperatures

D. 

diabetes mellitus

E. 

polycythemia

F. 

chronic bronchitis and emphysema

 

38.

Blood tests revealed a low hematocrit level, which explained why Mr. Jenkins had been feeling so tired and listless. A deficiency of red blood cells reduces the oxygen carrying capacity of the blood, a condition called ________. 
 

A. 

anemia

B. 

anoxia

C. 

polycythemia

D. 

hypoxia

E. 

leukemia

 

39.

Only 4 atoms of this trace element are present in hemoglobin, but they mark the 4 binding sites for oxygen. 
 

A. 

nitrogen

B. 

carbon

C. 

hydrogen

D. 

iron

E. 

none of these

 

40.

In an inherited disorder called hemochromatosis, the small intestine absorbs many times the normal amount of this element. 
 

A. 

iron

B. 

cobalt

C. 

thalium

D. 

calcium

E. 

none of these

 

41.

What iron storage disease is inherited and if left untreated, leads to a toxic buildup in body tissues? 
 

A. 

Parkinson's disease

B. 

Addison's disease

C. 

hemochromacytosis

D. 

Sickle cell disease

 

42.

What inherited disorder causes hemoglobin molecules to bend into an abnormal shape, blocking blood flow and severely impairing oxygen delivery to tissues? 
 

A. 

Parkinson's disease

B. 

Addison's disease

C. 

hemochromacytosis

D. 

Sickle cell disease

 

43.

What is biliverdin? 
 

A. 

a red-orange pigment molecule that is converted to carotene

B. 

a green pigment resulting from hemoglobin breakdown

C. 

a yellow pigment that results from the zinc-containing product of hemoglobin

D. 

the yellow pigment that gives urine its color

 

44.

Jaundice is caused by an accumulation of this substance, which is a product of erythrocyte breakdown.

 
 

A. 

bilirubin

B. 

biliverdin

C. 

biliholiday

 

45.

These phagocytic cells have segmented nuclei and make up more than half of all white blood cells. 
 

A. 

lymphocytes

B. 

granulocytes

C. 

agranulocytes

D. 

leukocytes

E. 

neutrophils

 

46.

These white blood cells usually have bilobed nuclei and cytoplasm filled with granules that appear deeply red in an acidic stain. 
 

A. 

eosinophil

B. 

basophil

C. 

monocyte

D. 

neutrophil

E. 

lymphocyte

 

47.

The normal range for this granulocyte is 1% - 3% of all circulating WBCs. 
 

A. 

neutrophil

B. 

lymphocyte

C. 

monocyte

D. 

eosinophil

E. 

basophil

 

48.

Granules in these WBCs appear very dark blue in a basic stain; these cells account for less than 1% of circulating WBCs. 
 

A. 

neutrophils

B. 

lymphocytes

C. 

monocytes

D. 

eosinophils

E. 

basophils

 

49.

These are the largest white blood cells (WBCs), make up 3% - 9% of circulating WBCs, and have a life span of weeks or even months. 
 

A. 

neutrophils

B. 

lymphocytes

C. 

monocytes

D. 

eosinophils

E. 

basophils

 

50.

These cells make up 25% - 33% of all circulating WBCs and are closest in size to RBCs. 
 

A. 

neutrophils

B. 

lymphocytes

C. 

monocytes

D. 

eosinophils

E. 

basophils

 

51.

Some of these WBCs may live for years. 
 

A. 

neutrophils

B. 

lymphocytes

C. 

monocytes

D. 

eosinophils

E. 

basophils

 

52.

Which type of white blood cells leave circulation and become macrophages? 
 

A. 

neutrophils

B. 

lymphocytes

C. 

monocytes

D. 

eosinophils

E. 

basophils

 

53.

What is the average life span of a granulocyte? 
 

A. 

4 months

B. 

30 days

C. 

2 weeks

D. 

12 hours

E. 

none of these

 

54.

Which below is NOT true of eosinophils? 
 

A. 

They are weakly phagocytic.

B. 

They are attracted to and can kill certain parasites.

C. 

They help control inflammation and allergy responses.

D. 

They become macrophages.

 

55.

How are white blood cells able to leave blood vessels and enter tissue spaces? 
 

A. 

osmotic pressure

B. 

diffusion

C. 

diapedesis

D. 

agglutination

 

56.

What is the function of the hormone thrombopoietin? 
 

A. 

It stimulates platelet formation.

B. 

It inhibits platelet formation.

C. 

It stimulates thrombus formation.

D. 

It inhibits megakaryocyte formation.

 

57.

What term below specifically refers to a condition of having too many white blood cells? 
 

A. 

lymphedema

B. 

leukopenia

C. 

leukocytosis

D. 

polycythemia

 

58.

What could a high white blood cell count indicate? 
 

A. 

leukemia

B. 

appendicitis

C. 

sickle cell anemia

D. 

a and b

E. 

a and c

 

59.

What term refers to a white cell count that is lower than normal? 
 

A. 

leukocytocis

B. 

polycythemia

C. 

leukopenia

D. 

thrombocytosis

E. 

hemolytic anemia

 

60.

What test reveals the percentage of each WBC present in a patient's blood sample? 
 

A. 

hematocrit

B. 

DIFF count

C. 

western blot

D. 

glucose tolerance

E. 

buffy coat analysis

 

61.

What is the function of a megakaryocyte? 
 

A. 

It is a cell from which all types of white blood cells develop.

B. 

It is a cell from which monocytes develop.

C. 

It is the stem cell from which all blood cells develop.

D. 

It is a cell that forms many platelets.

 

62.

Which substance is NOT an organic nutrient present in plasma? 
 

A. 

glucose

B. 

lipids

C. 

amino acids

D. 

calcium

 

63.

Which plasma component below is NOT a nonprotein nitrogenous substance? 
 

A. 

urea

B. 

uric acid

C. 

creatinine

D. 

keratin

 

64.

________ is the term for stopping bleeding. 
 

A. 

hemolysis

B. 

hemostasis

C. 

agglutination

D. 

hematomesis

E. 

homeostasis

 

65.

What event below could cause smooth muscle of a blood vessel to go into spasms? 
 

A. 

vessel injury

B. 

parasympathetic stimulation

C. 

formation of a blood clot

D. 

a deficiency of plasma globulins

 

66.

What is the major event in blood clotting? 
 

A. 

formation of collagen

B. 

formation of platelet plug

C. 

vasospasm

D. 

formation of fibrin

E. 

formation of plasmin

 

67.

Which statement is true about people with blood type A
 

A. 

They have anti-A and anti-Rh antibodies.

B. 

They have anti-B and anti-Rh antibodies.

C. 

They have anti-B and anti-O antibodies.

D. 

They have A antigens and Rh antigens.

E. 

They have B antigens.

 

68.

What blood group antigens are present in people whose blood type is O
 

A. 

Rh antigen

B. 

A antigen

C. 

B antigen

D. 

All of these

E. 

None of these

 

69.

What blood group antibodies are present in people whose blood type is O
 

A. 

anti-A antibodies

B. 

anti-B antibodies

C. 

Both anti-A and anti-B antibodies

D. 

Neither anti-A nor anti-B antibodies

 

70.

What happens when a person with anti-A antibodies receives a transfusion of type A blood? 
 

A. 

nothing

B. 

blood clot formation

C. 

agglutination

D. 

hemorrhage

 

71.

What two vitamins significantly influence red blood cell production and are essential for DNA synthesis? 
 

A. 

Vitamins A and D

B. 

Folic acid and vitamin B12

C. 

Vitamins A and C

D. 

Vitamins C and D

E. 

Folic acid and vitamin D

 

 


True / False Questions
 

72.

Blood is a type of epithelial tissue. 
 
True    False

 

73.

A red blood cell contains a large nucleus; it is thicker near the center and thin around the rim of the cell. 
 
True    False

 

74.

Vitamin B12 is important for the production of red blood cells because it is utilized in the synthesis of intrinsic factor. 
 
True    False

 

75.

A platelet plug is formed when fibrinogen is converted to fibrin. 
 
True    False

 

76.

Plasma contains fibrinogen; serum does not. 
 
True    False

 

77.

Persons with type AB blood are sometimes called universal donors. 
 
True    False

 

78.

Formed elements of the blood include proteins, cells, and cell fragments. 
 
True    False

 

79.

Plasma makes up more than half (55%) of the volume of blood. 
 
True    False

 

80.

Mature red blood cells cannot divide, do not synthesize hemoglobin and cannot conduct aerobic respiration. 
 
True    False

 

81.

Macrophages phagocytize old red blood cells and transport hemoglobin to the kidney for elimination. 
 
True    False

 

82.

A build up of bilirubin causes the yellowish coloration seen in jaundice. 
 
True    False

 

83.

Interleukins and colony stimulating factors stimulate white blood cell formation and differentiation.

 
 
True    False

 

84.

Normally, there are 5 different types of white blood cells in the circulating blood. 
 
True    False

 

85.

Neutrophils, eosinophils and basophils are called granulocytes. 
 
True    False

 

86.

As a rule, red blood cells are larger than white blood cells. 
 
True    False

 

87.

Monocytes, lymphocytes and platelets form the agranulocytes. 
 
True    False

 

88.

Basophils release chemicals that increase blood flow to injured tissues and promote inflammation. 
 
True    False

 

89.

Lymphocytes function as phagocytes against bacteria. 
 
True    False

 

90.

Plasma is about 50% water and 50% dissolved substances. 
 
True    False

 

91.

Albumin, collagen and fibrinogen are the three main types of plasma proteins. 
 
True    False

 

92.

Plasma proteins serve as solutes that attract and hold water in the bloodstream, which helps maintain osmotic balance. 
 
True    False

 

93.

Platelets function to repair breaks in blood vessels and clot the blood. 
 
True    False

 

94.

Most plasma proteins are produced by the liver. 
 
True    False

 

95.

Oxygen, carbon dioxide and sodium are the 3 main gases dissolved in the blood. 
 
True    False

 

96.

Glucose is a plasma electrolyte. 
 
True    False

 

97.

Some plasma electrolytes function to maintain osmotic pressure and also regulate blood pH. 
 
True    False

 

98.

Platelets forming a platelet plug release serotonin, which causes vessel walls to dilate. 
 
True    False

 

99.

Agglutination has the same meaning as coagulation. 
 
True    False

 

100.

Some clotting factors actually promote clot formation but others inhibit it. 
 
True    False

 

101.

A thrombus is an abnormal clot that forms in a vessel; if the clot or a part of it breaks away into the circulation, it becomes an embolus. 
 
True    False

 

102.

Calcium is a clotting factor. 
 
True    False

 

 


Fill in the Blank Questions
 

103.

In an adult, red blood cells are produced primarily in the __________. 
 
________________________________________

 

104.

The hormone released from the kidneys that promotes the production of red blood cells is ________. 
 
________________________________________

 

105.

Vitamin B12 is important for the production of red blood cells because it is utilized in the synthesis of ___________. 
 
________________________________________

 

106.

When hemoglobin molecules are decomposed, a greenish pigment called ________ is formed. 
 
________________________________________

 

107.

Normally the most common type of leukocyte in a blood sample is the ________. 
 
________________________________________

 

108.

An abnormally low white blood cell count is called ________. 
 
________________________________________

 

109.

The test in which the percentages of various types of leukocytes in a blood sample is determined is the ________ white blood cell count. 
 
________________________________________

 

110.

The most abundant type of plasma protein is __________.  
 
________________________________________

 

111.

__________ is the term used to describe the stoppage of bleeding by any one of several means.  
 
________________________________________

 

112.

A clot that breaks loose and travels in the blood is called a(n) __________. 
 
________________________________________

 

113.

The clumping of red blood cells that occurs when transfused blood is of an incompatible type is called ________. 
 
________________________________________

 


Document Information

Document Type:
DOCX
Chapter Number:
12
Created Date:
Aug 21, 2025
Chapter Name:
Chapter 12 Blood
Author:
David Shier

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