Test Bank Chapter 36 Harris Epidemiology Of Lymphoma - Test Bank | Epidemiology of Chronic Disease 2e by Harris by Randall E. Harris. DOCX document preview.

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Test Bank Chapter 36 Harris Epidemiology Of Lymphoma

Chapter 36. Epidemiology of Lymphoma

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True/False Questions

  1. During 2018, 509,590 new cases of non-Hodgkin’s lymphoma were diagnosed in the world population, and 248,724 individuals died from the disease.
  2. Nearly 75% of deaths from lymphoma occur after the age of 65 years.
  3. Age-adjusted rates of non-Hodgkin’s lymphoma dramatically increased in the United States population during the period 1970-1995.
  4. The annual incidence of non-Hodgkin’s lymphoma in the United States increased until about 1995 but then subsequently declined, coinciding with the decline in rates of HIV disease.
  5. Two principal biological phenomena involved in the genesis of lymphoma are immunosuppression and antigenic stimulation of lymphocytes.
  6. Familial lymphomas are common and account for more than 25% of all cases.
  7. Lymphomas are genetically characterized by the presence of heritable chromosomal translocations.
  8. The extraordinarily high risk for the development of non-Hodgkin’s lymphoma among individuals who are HIV-seropositive has led to its recognition as an AIDS-defining condition.
  9. Epstein Barr Virus (EBV) is detected in nearly all cases of Burkitt’s lymphoma.
  10. The Reed-Sternberg cell of Hodgkin’s disease is derived from macrophages.

Multiple Choice Questions

  1. Hodgkin’s disease is characterized by the presence of what cells?
    1. Reed-Sternberg cells
    2. Lymphoblasts
    3. Eosinophils
    4. Macrophages
  2. Multiple myeloma is a malignancy of what cell population?
    1. Immature B lymphocytes
    2. lymphocytes
    3. Plasma cells
    4. Macrophages
  3. What ethnic population has the highest rates of multiple myeloma in the world?
    1. Caucasian Americans
    2. African Americans
    3. Hispanic Americans
    4. Asian Americans
  4. What gene has been found to increase the risk of multiple myeloma among African Americans by more than 5-fold?
    1. Mutant P53
    2. Mutant BRCA-1
    3. Mutant BRCA-2
    4. HLA-Cw2
  5. What biomarker shows value as a biomarker of impending multiple myeloma?
    1. Carcinoembryonic Antigen (CEA)
    2. Alpha-Fetoprotein
    3. Monoclonal Gammopathy of Undetermined Significance (MGUS)
    4. C Reactive Protein (CRP)
  6. Waldenström's macroglobulinemia is a rare condition characterized by a monoclonal gammopathy of:
    1. immunoglobulin M (IgM).
    2. immunoglobulin A (IgA).
    3. immunoglobulin G (IgG).
    4. undetermined significance (MGUS).
  7. The trisomy of Burkitt’s lymphoma includes all of the following except:
    1. malaria.
    2. EBV infection.
    3. c-myc translocation to one of the immunoglobulin loci.
    4. HIV disease.
  8. All of the following groups of patients have high rates of non-Hodgkin’s lymphoma except:
    1. patients with HIV infection.
    2. post-transplant patients treated with immunosuppressive drugs.
    3. patients with autoimmune conditions or cancer who received immunosuppressive chemotherapy.
    4. patients taking NSAIDs.
  9. What percentage of non-Hodgkin’s lymphomas are derived from B lymphocytes?
    1. 50-60%
    2. 60-70%
    3. 70-80%
    4. 80-90%
  10. The highest mortality rates from non-Hodgkin’s lymphoma are observed in the populations of:
    1. North America.
    2. South America.
    3. Central Africa.
    4. South East Asia.

Essay Questions

  1. Describe the different forms of lymphoma.

  1. Briefly discuss the global epidemiology of non-Hodgkin’s lymphoma.

  1. Describe risk factors for non-Hodgkin’s lymphoma.

  1. Describe the trisomy of Burkitt’s lymphoma.

  1. Discuss the global epidemiology of Hodgkin’s lymphoma.

  1. Discuss the characteristic features of multiple myeloma.

  1. Discuss the global epidemiology of multiple myeloma.

  1. Define and discuss Waldenström's macroglobulinemia.

  1. Describe strategies for the prevention of lymphoma.

  1. Describe new developments in the treatment of lymphoma.

Document Information

Document Type:
DOCX
Chapter Number:
36
Created Date:
Aug 21, 2025
Chapter Name:
Chapter 36 Epidemiology Of Lymphoma
Author:
Randall E. Harris

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