Ch9 | Exam Questions – The Immune System and Mechanisms of

Human Biology: Concepts and Current Issues, 8e (Johnson)

Chapter 9 The Immune System and Mechanisms of Defense

9.1 Multiple-Choice Questions

1) Ebola virus can be transmitted via

A) fruit fallen from a tree.

B) direct contact with bodily fluids of an infected person.

C) agriculture/crops in an epidemic area.

D) any contact, like a handshake.

Topic: Sec. 9.0

Bloom's: Remembering/Understanding

LO: 9.1

GLO: G1

2) Body defenses that respond to generalized tissue damage and many common pathogens are referred to as

A) phagocytic.

B) antipathogenic responses.

C) nonspecific mechanisms.

D) lymphomas.

E) specific mechanisms.

Topic: Sec. 9.0

Bloom's: Remembering/Understanding

LO: 9.4

GLO: G1

3) Which one of the following diseases is caused by a virus?

A) rabies

B) Lyme disease

C) syphilis

D) toxic shock syndrome

E) tuberculosis

Topic: Sec. 9.1

Bloom's: Remembering/Understanding

LO: 9.1

GLO: G1

4) Bacteria are helpful to humans in many ways, including all of the following EXCEPT which one?

A) production of antibiotics

B) breakdown of raw sewage

C) digestion of cellulose in the human intestine

D) production of soy sauce

E) production of vitamins for the human body

Topic: Sec. 9.1

Bloom's: Remembering/Understanding

LO: 9.1

GLO: G1

5) When comparing viruses and bacteria, which one of the following statements is CORRECT?

A) Viruses are larger than bacteria.

B) Viruses are pathogens; bacteria are decomposers.

C) Viruses have membrane-bound organelles; bacteria do not have membrane-bound organelles.

D) Viruses and bacteria are both able to reproduce on their own.

E) Viruses and bacteria both contain genetic material.

Topic: Sec. 9.1

Bloom's: Remembering/Understanding

LO: 9.1

GLO: G1

6) The bubonic plague epidemic that swept through Europe between 1348 and 1350 A.D. was induced by a(n)

A) virus.

B) prion.

C) protozoan.

D) bacterium.

E) unidentified eukaryotic organism.

Topic: Sec. 9.1

Bloom's: Remembering/Understanding

LO: 9.1

GLO: G1

7) Once a prion enters a nerve cell, it essentially

A) assumes the correct folding orientation for the protein.

B) stops the cascade of misfolding events associated with adjacent cells.

C) becomes self-propagating, causing misfolding of nearby normal proteins.

D) differentiates into a nonreplicating virus.

E) differentiates into a replicating virus.

Topic: Sec. 9.1

Bloom's: Remembering/Understanding

LO: 9.1

GLO: G1

8) Antibiotics are most likely to be effective in the treatment of infections caused by

A) bacteria.

B) viruses.

C) parasitic worms.

D) lice and ticks.

E) prions.

Topic: Sec. 9.1

Bloom's: Remembering/Understanding

LO: 9.1

GLO: G1

9) Which of the following is TRUE regarding lymph nodes?

A) They are located only in the digestive tract and neck.

B) They remove microorganisms and abnormal cells from the lymph and return them to blood circulation.

C) Macrophages but not lymphocytes can be found within lymph nodes.

D) They filter lymph fluid, trapping microorganisms and abnormal cells.

E) Lymph flows from the lymph vessels to the urinary system.

Topic: Sec. 9.2

Bloom's: Remembering/Understanding

LO: 9.2

GLO: G1

10) Which one of the following is TRUE regarding the spleen?

A) It is located in the lower portion of the thoracic cavity.

B) Red pulp of the spleen stores excess blood.

C) White pulp of the spleen contains macrophages that kill microorganisms circulating in the lymph.

D) Red pulp of the spleen contains primarily lymphocytes.

E) The spleen has the same functions as the tonsils.

Topic: Sec. 9.2

Bloom's: Remembering/Understanding

LO: 9.2

GLO: G1

11) Which one of the following is/are located in the tonsils to filter out many of the microorganisms that enter the throat?

A) thymus

B) adenoids

C) lymphocytes

D) platelets

E) red blood cells

Topic: Sec. 9.2

Bloom's: Remembering/Understanding

LO: 9.2

GLO: G1

12) Skin is able to prevent most microorganisms from entering the body by

A) producing alkaline secretions.

B) having keratin in the uppermost layer.

C) production of antibodies.

D) the adhesion junction in the skin preventing bacteria from entering.

E) releasing macrophages on the skin surface.

Topic: Sec. 9.3

Bloom's: Remembering/Understanding

LO: 9.3

GLO: G1

13) Why do some physicians advise patients with a bladder infection to drink a lot of cranberry juice?

A) Cranberry juice contains chemicals that kill viruses and bacteria.

B) The increased volume of fluid in the bladder causes bacterial cells to burst as they absorb the excess fluid.

C) Cranberry juice makes the urine more acidic, decreasing the rate at which microorganisms can grow and reproduce.

D) Cranberry juice increases the efficiency of urine production by the kidneys.

E) Cranberry juice enhances the action of phagocytic cells.

Topic: Sec. 9.3

Bloom's: Applying/Analyzing

LO: 9.3

GLO: G2

14) All of the following represent physical and/or chemical barriers that form the body's first line of defense against pathogens EXCEPT which one?

A) tears

B) resident bacteria

C) skin surface

D) earwax

E) antibodies

Topic: Sec. 9.3

Bloom's: Remembering/Understanding

LO: 9.3

GLO: G1

15) The release of chemicals from injured cells triggers histamine release from

A) macrophages.

B) B cells.

C) neutrophils.

D) phagocytes.

E) mast cells.

Topic: Sec. 9.4

Bloom's: Remembering/Understanding

LO: 9.4

GLO: G1

16) The following is a list of steps involved in the process of phagocytosis. Which of the following answers indicates these steps in the CORRECT order?

1. Lysosome fuses with the vesicle containing a foreign cell.

2. Wastes from the foreign cell are removed.

3. The foreign cell is surrounded by the cell membrane of the phagocyte.

4. Lysosomal enzymes break down the foreign cell.

5. The foreign cell is contained within a vesicle.

A) 5, 3, 1, 4, 2

B) 3, 5, 2, 1, 4

C) 3, 5, 1, 4, 2

D) 2, 4, 1, 5, 3

E) 3, 1, 5, 4, 2

Topic: Sec. 9.4

Bloom's: Remembering/Understanding

LO: 9.4

GLO: G1

17) Which of the following leukocytes is most likely to be directly involved in the destruction of flukes (a parasitic flatworm)?

A) natural killer cells

B) eosinophils

C) neutrophils

D) B lymphocytes

E) basophils

Topic: Sec. 9.4

Bloom's: Remembering/Understanding

LO: 9.4

GLO: G1

18) Which of the following leukocytes kills its target cells, such as cancer cells or virus-infected cells, by releasing chemicals that break down the target cell membrane?

A) natural killer cells

B) B lymphocytes

C) basophils

D) T lymphocytes

E) macrophages

Topic: Sec. 9.4

Bloom's: Remembering/Understanding

LO: 9.4

GLO: G1

19) All of the following are ways in which a mild fever participates as part of the body's second line of defense and aids the body EXCEPT

A) increasing the metabolic rate of body cells.

B) speeding up defense reactions.

C) increasing the rate of tissue repair.

D) creating an inhospitable internal environment for pathogenic bacteria.

E) enhancing the secretion of antibodies by plasma cells.

Topic: Sec. 9.4

Bloom's: Remembering/Understanding

LO: 9.4

GLO: G1

20) All of the following are involved in the inflammatory response EXCEPT

A) antibodies.

B) mast cells.

C) histamine.

D) basophils.

E) phagocytes.

Topic: Sec. 9.4

Bloom's: Applying/Analyzing

LO: 9.4

GLO: G2

21) Which of the following are proteins in the blood that can be activated to lyse bacterial cells, mark other bacterial cells for destruction, and enhance inflammation?

A) albumins

B) antibodies

C) complement

D) interferons

E) lymphokines

Topic: Sec. 9.4

Bloom's: Remembering/Understanding

LO: 9.4

GLO: G1

22) Viral-infected human cells often send out special proteins that serve as an early warning system to uninfected cells. In response, the uninfected cells develop antiviral proteins that protect them. The early warning proteins sent out by viral-infected cells are

A) complement.

B) interferon.

C) antibodies.

D) antigens.

E) antibiotics.

Topic: Sec. 9.4

Bloom's: Remembering/Understanding

LO: 9.4

GLO: G1

23) Which of the following is associated with the specific defenses of the body?

A) cell-mediated immunity

B) phagocytosis

C) interferons

D) the inflammatory response

E) the complement system

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

24) Antibodies are classified by size, location, and function, and which one of the following represents the most common type of immunoglobulin?

A) IgM

B) IgG

C) IgA

D) IgD

E) MHC

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

25) Which one type of cells is responsible for producing and releasing antibodies?

A) red bone marrow

B) B lymphocytes

C) T lymphocytes

D) macrophages

E) natural killer cells

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

26) Which one of the following is characteristic of T lymphocytes but NOT B lymphocytes?

A) direct attack of antigen-bearing cells

B) production of immunoglobulins

C) maturation in the red bone marrow

D) production of plasma cells

E) antibody-mediated immunity

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5b

GLO: G1

27) The advantage of having memory cells in specific defenses is that

A) they remain in an active state, continuously producing antibodies.

B) if exposed to an antigen a second time, they quickly become plasma cells.

C) they prevent production of other proteins so that antibodies can be produced.

D) they produce antibodies and can become phagocytic.

E) they prevent viruses from entering the body a second time.

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5b

GLO: G1

28)

Identify the figure above.

A) complement

B) antibody

C) antigen

D) interferon

E) pyrogen

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5b

GLO: G1

29) Once a macrophage engulfs a bacterium, what happens to the foreign cell?

A) It is released into the lymph system for removal from the body.

B) It is released into the digestive tract for removal from the body.

C) The macrophage is attacked by antibodies, killing the cell and bacterium.

D) Antibodies penetrate the macrophage to lyse the bacterial cell.

E) The bacterium is killed by digestive enzymes released from lysosomes.

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

30) Which of the following antibodies would most likely be involved with the immune response against a microorganism entering the digestive or reproductive tract?

A) IgA

B) IgD

C) IgG

D) IgM

E) IgE

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

31) Which of the following classes of antibodies activates the inflammatory response by causing the release of histamine?

A) IgG

B) IgE

C) IgD

D) IgM

E) IgA

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

32) During cytotoxic T cell attack of a target cell, which one of the following is released to pierce the cell membrane of the foreign cell, which ultimately kills the target cell?

A) interferon

B) eosinophil

C) histamine

D) perforin

E) antibody

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

33) Which one of the following is correct regarding the structure of an antibody?

A) An antibody is made up of two polypeptide chains linked by hydrogen bonds.

B) The four polypeptide chains that make up an antibody molecule are linked by disulfide bonds.

C) The constant regions of the polypeptides in an antibody form antigen-binding sites.

D) Only one polypeptide in an antibody has a constant region and a variable region.

E) The polypeptides making up an antibody are connected by hydrogen bonds.

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

34) Which one of the following types of T cells is a critical component of the immune system because it stimulates and enhances the activity of other components of the immune system?

A) T suppressor cell

B) T memory cell

C) T helper cell

D) cytotoxic T cell

E) natural killer cells

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

35) Which one of the following enables T helper cells to stimulate and activate other cells of the immune response?

A) interferon

B) cytokines

C) antibodies

D) complement

E) histamine

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

36) Which immune system cell must be presented with antigen by an antigen-presenting cell such as a macrophage, in order to become appropriately activated?

A) B lymphocyte

B) plasma cell

C) macrophage

D) T lymphocyte

E) natural killer cell

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5b

GLO: G1

37)

The figure above illustrates antibody titers produced during a primary and secondary immune response. All of the following statements about the primary and secondary immune response are correct EXCEPT which one?

A) Antibody is produced at a much higher rate during the secondary immune response.

B) The antibody level produced in the secondary response is three times greater than that produced during the primary immune response.

C) There is a lag time between antigen exposure and antibody production in the primary immune response that is not seen in the secondary immune response.

D) The difference between the two responses is due to the presence of memory cells during the secondary response.

E) Antibody levels stay elevated for a longer time following a secondary response.

Topic: Sec. 9.5

Bloom's: Applying/Analyzing

LO: 9.5b

GLO: G2

38) Which one of the following best explains why people get so many colds in their lifetime?

A) The immune system has a hard time identifying the viruses that cause the colds.

B) The viruses that cause these colds constantly produce new antibodies, which cause the symptoms.

C) These individuals do not produce enough white blood cells.

D) The viruses that cause colds evolve rapidly, which results in a change in their antigenic structure.

E) The B cells of these individuals destroy their T cells.

Topic: Sec. 9.6

Bloom's: Applying/Analyzing

LO: 9.6

GLO: G2

39) Vaccines contain

A) memory cells against the pathogen.

B) antigens of the pathogen.

C) antibodies of the pathogen.

D) lymphokines.

E) T cells programmed to attack the pathogen.

Topic: Sec. 9.7

Bloom's: Remembering/Understanding

LO: 9.7

GLO: G1

40) Passive immunity differs from active immunity in that passive immunity

A) causes long-term immunity.

B) involves the administration of preformed antibodies.

C) results in the production of antibodies.

D) is not effective against a preexisting condition.

E) results in the production of memory cells.

Topic: Sec. 9.7

Bloom's: Remembering/Understanding

LO: 9.7

GLO: G1

41) An individual with an uncertain vaccine history has been brought to the emergency room after receiving severe lacerations in an accident with farm machinery. In addition to administering a tetanus toxoid vaccine, he is given a shot of tetanus immune globulin (TIG), a form of passive immunization. Why are both necessary?

A) The tetanus vaccine provides immediate protection, and the tetanus immune globulin provides long-term protection.

B) The doctor is not sure which will work faster in this patient so decides to administer both.

C) The tetanus immune globulin is given only when there are severe injuries and a high risk of infection.

D) Tetanus immune globulin is always given along with the tetanus vaccine.

E) The tetanus immune globulin provides immediate, short-term protection, and the tetanus vaccine provides long-term protection.

Topic: Sec. 9.7

Bloom's: Applying/Analyzing

LO: 9.7

GLO: G2

42) Which one of the following would result in passive immunity?

A) vaccination

B) past occurrence of an infection or disease

C) production of memory cells

D) movement of antibodies across the placenta from mother to child

E) stimulation of T cells and B cells by an antigen

Topic: Sec. 9.7

Bloom's: Applying/Analyzing

LO: 9.7

GLO: G2

43) All of the following are used in making monoclonal antibodies EXCEPT which one?

A) mouse T cells from thymus

B) mouse B cells from spleen

C) specific antigen injected into mouse

D) myeloma (cancer) cells

E) cell culture media for hybridoma cells

Topic: Sec. 9.7

Bloom's: Applying/Analyzing

LO: 9.7

GLO: G2

44) Antibiotics kill bacterial cells but do not (usually) damage human cells by taking advantage of the difference between human and bacterial cells. These differences include

A) bacterial cells have cell walls, human cells do not.

B) bacterial ribosomes are larger than those of humans.

C) protein synthesis in bacteria is identical to that in human cells.

D) bacterial cells have a cell membrane, human cells do not.

E) human and bacterial DNA are enclosed in a nucleus.

Topic: Sec. 9.7

Bloom's: Remembering/Understanding

LO: 9.7

GLO: G1

45) All of the following are routinely done to assure a successful organ transplant and minimize the chance of organ rejection EXCEPT which one?

A) match the ABO blood types of donor and recipient

B) match the MHC tissue types of donor and recipient

C) irradiate the recipient to knock out his or her immune system prior to the transplant

D) give the recipient immunosuppressive drugs to suppress reactions against the transplanted tissue

E) give the recipient antibiotics to control any infections

Topic: Sec. 9.8

Bloom's: Remembering/Understanding

LO: 9.8

GLO: G1

46) Any substance that produces an inappropriate response of the immune system is referred to as a(an)

A) allergen.

B) antibody.

C) plasma cell.

D) allergy.

E) perforin.

Topic: Sec. 9.9

Bloom's: Remembering/Understanding

LO: 9.9

GLO: G1

47) Lupus erythematosus is an autoimmune disorder in which the body attacks

A) its own connective tissue.

B) the brain.

C) the spleen.

D) its own antibodies.

E) heart tissue.

Topic: Sec. 9.9

Bloom's: Remembering/Understanding

LO: 9.9

GLO: G1

48) All of the following are involved in the generation of an allergic response EXCEPT which one?

A) allergen

B) IgE

C) IgG

D) mast cells and basophils

E) histamine

Topic: Sec. 9.9

Bloom's: Applying/Analyzing

LO: 9.9

GLO: G2

49) HIV is classified as a retrovirus because

A) it infects only cells with a CD4 receptor.

B) it makes a DNA copy of its RNA once inside the host cell.

C) this virus is composed of two cells surrounded by a lipoprotein coat.

D) it reverts to an inactive form when it infects B lymphocytes.

E) it causes the production of HIV antibodies.

Topic: Sec. 9.10

Bloom's: Remembering/Understanding

LO: 9.10

GLO: G1

50) Which of the following body fluids does not transmit HIV from human to human?

A) blood

B) semen

C) saliva

D) vaginal fluid

E) breast milk

Topic: Sec. 9.10

Bloom's: Remembering/Understanding

LO: 9.10

GLO: G1

51) Which of the following is TRUE regarding HIV and AIDS?

A) Most of the people infected with HIV live in South America, where the disease originated.

B) Approximately 100,000 people worldwide are newly diagnosed with HIV each day.

C) Due to improved availability of drugs combating HIV in the United States, there is an increase in the life span of people living with AIDS.

D) Symptoms of AIDS appear quickly after HIV detection.

E) More than 95% of people living with HIV will die within five years.

Topic: Sec. 9.10

Bloom's: Remembering/Understanding

LO: 9.10

GLO: G1

52) Which of the following best describes Phase I of HIV infection?

A) T cell count of 100 per cubic millimeter of blood

B) presence of an opportunistic infection

C) swollen lymph nodes, chills, fever, body aches

D) onset of AIDS

E) absence of HIV antibodies

Topic: Sec. 9.10

Bloom's: Remembering/Understanding

LO: 9.10

GLO: G1

53)

Referring to the figure above, the progression from Phase II HIV infection to Phase III is marked by

A) a high fever and swollen lymph nodes.

B) a drop in the helper T cell count to less than 200/mm3.

C) the complete absence of antibodies to HIV.

D) decreasing HIV in the blood.

E) helper T cell numbers recovering from an initial drop.

Topic: Sec. 9.10

Bloom's: Applying/Analyzing

LO: 9.10

GLO: G1

9.2 True/False Questions

1) Bacterial pathogens cause symptoms of a disease by invading host cells or by producing toxins that damage host cells.

Topic: Sec. 9.1

Bloom's: Remembering/Understanding

LO: 9.1

GLO: G1

2) Prions are infectious proteins that cause normal proteins in the brain to misfold.

Topic: Sec. 9.1

Bloom's: Remembering/Understanding

LO: 9.1

GLO: G1

3) Viral infections can usually be treated with antibiotics.

Topic: Sec. 9.1

Bloom's: Remembering/Understanding

LO: 9.1

GLO: G1

4) Lymph nodes filter the blood and remove bacteria and other invading microorganisms that may have entered the bloodstream.

Topic: Sec. 9.2

Bloom's: Remembering/Understanding

LO: 9.2

GLO: G1

5) The thymus gland, which is responsible for the development of T cells, stops growing during adolescence and shrinks as one grows into adulthood.

Topic: Sec. 9.2

Bloom's: Remembering/Understanding

LO: 9.2

GLO: G1

6) Tears and saliva contain the enzyme dermicidin, which is effective in preventing bacteria from entering the human body.

Topic: Sec. 9.3

Bloom's: Remembering/Understanding

LO: 9.3

GLO: G1

7) The bacteria that normally live on the mucous membranes of the digestive tract and vagina provide protection against infection with harmful disease-producing microorganisms.

Topic: Sec. 9.3

Bloom's: Remembering/Understanding

LO: 9.3

GLO: G1

8) The best way to reduce bacterial pathogens in the bloodstream is to reduce a fever as quickly as possible.

Topic: Sec. 9.4

Bloom's: Remembering/Understanding

LO: 9.4

GLO: G1

9) Histamine is released by neutrophils to induce an inflammation response when tissues become damaged.

Topic: Sec. 9.4

Bloom's: Remembering/Understanding

LO: 9.4

GLO: G1

10) The first type of white blood cell to arrive at the site of an infection is the eosinophil.

Topic: Sec. 9.4

Bloom's: Remembering/Understanding

LO: 9.4

GLO: G1

11) One role of MHC proteins is that they serve as self markers to the human immune system.

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5b

GLO: G1

12) The best way to defend the body from a viral infection is to prevent the infection by using a vaccine.

Topic: Sec. 9.7

Bloom's: Remembering/Understanding

LO: 9.7

GLO: G1

13) When considering transfusions or transplants, it is more difficult to match blood than to match tissue types because blood cells have more self markers on their surface.

Topic: Sec. 9.8

Bloom's: Remembering/Understanding

LO: 9.8

GLO: G1

14) Individuals infected with HIV produce antibodies, but these antibodies do not prevent progression to Phase II and Phase III of infection.

Topic: Sec. 9.10

Bloom's: Applying/Analyzing

LO: 9.10

GLO: G5

9.3 Matching Questions

The human body uses three lines of defense to protect against pathogens. Match each of the following categories of defense to the type of cell or mechanism involved in the defense. Answers may be used more than once.

A) physical or chemical barrier

B) specific defense mechanism

C) nonspecific defense mechanism

1) cytotoxic T cells

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

2) inflammation

Topic: Sec. 9.4

Bloom's: Remembering/Understanding

LO: 9.4

GLO: G1

3) acidic pH of skin

Topic: Sec. 9.3

Bloom's: Remembering/Understanding

LO: 9.3

GLO: G1

4) natural killer cells

Topic: Sec. 9.4

Bloom's: Remembering/Understanding

LO: 9.4

GLO: G1

5) release of interferons

Topic: Sec. 9.4

Bloom's: Remembering/Understanding

LO: 9.4

GLO: G1

6) earwax

Topic: Sec. 9.3

Bloom's: Remembering/Understanding

LO: 9.3

GLO: G1

7) production of antibodies by plasma cells

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

8) release of perforin and granzyme by cytotoxic cells

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

Answers: 1) B 2) C 3) A 4) C 5) C 6) A 7) B 8) B

Match each component of the lymphatic system to its function.

A) tonsil

B) lymphatic vessel

C) spleen

D) lymph node

E) thymus

9) transports lymph in the body

Topic: Sec. 9.2

Bloom's: Remembering/Understanding

LO: 9.2

GLO: G1

10) removes microorganisms and old red blood cells from the blood

Topic: Sec. 9.2

Bloom's: Remembering/Understanding

LO: 9.2

GLO: G1

11) filters out microorganisms that enter the throat by food or air

Topic: Sec. 9.2

Bloom's: Remembering/Understanding

LO: 9.2

GLO: G1

12) secretes hormones important in the maturation of T cells

Topic: Sec. 9.2

Bloom's: Remembering/Understanding

LO: 9.2

GLO: G1

13) filters microorganisms and cellular debris from lymph

Topic: Sec. 9.2

Bloom's: Remembering/Understanding

LO: 9.2

GLO: G1

Answers: 9) B 10) C 11) A 12) E 13) D

Match each of the following T lymphocytes to its description.

A) helper T cells

B) cytotoxic T cells

C) memory T cells

14) migrate through blood and lymph, directly attacking and destroying foreign cells

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

15) activate the immune system when an antigen reenters the body

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5b

GLO: G1

16) stimulate the immune system by secreting lymphokines and interleukins; they activate B lymphocytes and macrophages

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

17) primary target of HIV

Topic: Sec. 9.10

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

Answers: 14) B 15) C 16) A 17) A

Match each of the following disorders associated with the immune system to its description.

A) acquired immunodeficiency syndrome (AIDS)

B) severe combined immunodeficiency disease (SCID)

C) rheumatoid arthritis

D) allergy

E) lupus erythematosus

18) an autoimmune disorder affecting the synovial membrane of the joints

Topic: Sec. 9.9

Bloom's: Remembering/Understanding

LO: 9.9

GLO: G1

19) an inherited disorder characterized by insufficient numbers of lymphocytes to fight an infection

Topic: Sec. 9.10

Bloom's: Remembering/Understanding

LO: 9.10

GLO: G1

20) an inappropriate response to a nonpathogenic substance

Topic: Sec. 9.9

Bloom's: Remembering/Understanding

LO: 9.9

GLO: G1

21) an autoimmune disorder affecting connective tissue

Topic: Sec. 9.9

Bloom's: Remembering/Understanding

LO: 9.9

GLO: G1

22) a disease caused by HIV infection; results in irreparable damage to the immune system

Topic: Sec. 9.10

Bloom's: Remembering/Understanding

LO: 9.10

GLO: G1

Answers: 18) C 19) B 20) D 21) E 22) A

9.4 Short Answer Questions

1) Bacterial infections are generally treated with ________.

Topic: Sec. 9.1

Bloom's: Remembering/Understanding

LO: 9.1

GLO: G1

2) Bacteria are classified as ________ cells because they do not have a nucleus or other membrane-bound organelles.

Topic: Sec. 9.1

Bloom's: Remembering/Understanding

LO: 9.1

GLO: G1

3) Microbes that cause disease are referred to as ________.

Topic: Sec. 9.1

Bloom's: Remembering/Understanding

LO: 9.1

GLO: G1

4) Microorganisms and cellular debris are removed from lymph by the ________ and from blood by the ________.

Topic: Sec. 9.2

Bloom's: Remembering/Understanding

LO: 9.2

GLO: G1

5) The ________ are lymphatic tissues that protect the throat.

Topic: Sec. 9.2

Bloom's: Remembering/Understanding

LO: 9.2

GLO: G1

6) Tears and saliva contain ________, an enzyme that kills bacteria.

Topic: Sec. 9.2

Bloom's: Remembering/Understanding

LO: 9.2

GLO: G1

7) Helicobacter pylori can survive the acidic conditions of the human stomach and have been found to cause the development of stomach ________.

Topic: Sec. 9.2

Bloom's: Remembering/Understanding

LO: 9.2

GLO: G1

8) The two major types of phagocytic cells are the ________ and the ________.

Topic: Sec. 9.3

Bloom's: Remembering/Understanding

LO: 9.3

GLO: G1

9) Inflammation generally results when tissues become damaged and ________ cells respond by releasing histamine.

Topic: Sec. 9.4

Bloom's: Remembering/Understanding

LO: 9.4

GLO: G1

10) Chemicals released by macrophages that cause the onset of a fever are called ________.

Topic: Sec. 9.4

Bloom's: Remembering/Understanding

LO: 9.4

GLO: G1

11) B lymphocytes mature in the ________.

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

12) Cell-mediated immunity involves the activity of ________ lymphocytes.

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

13) The unique set of proteins located on the surface of cells that distinguish one organism from another are the ________.

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5b

GLO: G1

14) Plasma cells and memory cells are types of ________ lymphocytes; both types of cells secrete proteins called ________ as part of the immune response.

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

15) The ________ class of immunoglobulins is the most common type and is the only type that can cross the placenta to pass on the mother's acquired immunity to the developing fetus.

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

16) While T lymphocytes are maturing, each of them develops one of two sets of proteins on their cell surface. These proteins are known as ________ and ________.

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

17) T cells are activated by macrophages and activated B cells, which fulfill this role by acting as ________.

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

18) The only T lymphocyte that directly attacks and destroys other cells is the ________ T cell.

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

19) Helper T cells release ________, molecules that stimulate the activity of other T cells and macrophages; these chemicals stimulate inflammation as well.

Topic: Sec. 9.5

Bloom's: Remembering/Understanding

LO: 9.5a

GLO: G1

20) The human body's first exposure to an antigen generates a primary ________ response.

Topic: Sec. 9.6

Bloom's: Remembering/Understanding

LO: 9.6

GLO: G1

21) An immunization that uses prepared antibodies from a human or animal donor and that does not provide long-lasting protection is called ________ immunity.

Topic: Sec. 9.7

Bloom's: Remembering/Understanding

LO: 9.7

GLO: G1

22) Drugs that kill or inhibit bacteria are known as ________.

Topic: Sec. 9.7

Bloom's: Remembering/Understanding

LO: 9.7

GLO: G1

23) Following transplant surgery, a patient is given ________ drugs that block the action of the immune response against the transplanted organ.

Topic: Sec. 9.8

Bloom's: Remembering/Understanding

LO: 9.8

GLO: G1

24) Symptoms of an allergic reaction such as increased secretion of mucus, swelling, and pain are due to the release of ________ from mast cells.

Topic: Sec. 9.9

Bloom's: Remembering/Understanding

LO: 9.9

GLO: G1

25) A life-threatening allergic reaction (difficulty in breathing, fall in blood pressure, severe stomach cramps) is known as ________.

Topic: Sec. 9.9

Bloom's: Remembering/Understanding

LO: 9.9

GLO: G1

26) A condition that results when the immune system produces antibodies and cytotoxic T cells against its own cells is a(n) ________ disorder.

Topic: Sec. 9.9

Bloom's: Remembering/Understanding

LO: 9.9

GLO: G1

27) Infection by HIV can eventually lead to the development of a condition called ________, which is diagnosed when the T helper cell count drops below ________.

Topic: Sec. 9.10

Bloom's: Remembering/Understanding

LO: 9.10

GLO: G1

28) ________ primarily targets T helper cells of the immune system.

Topic: Sec. 9.10

Bloom's: Remembering/Understanding

LO: 9.10

GLO: G1

9.5 Essay Questions

1) If you travel through an airport during a major holiday season, you are very likely exposed to a number of potential pathogens. Describe some of the first lines of defense that your body uses to keep these pathogens out of your body.

Topic: Sec. 9.3

Bloom's: Applying/Analyzing

LO: 9.3

GLO: G1

2) During a bacterial infection, the human body usually responds by having an elevated body temperature or a fever. Most over-the-counter cold medications indicate that they contain a fever suppressant. Explain why this is not always good for the treatment of a cold or infection.

Topic: Sec. 9.4

Bloom's: Applying/Analyzing

LO: 9.4

GLO: G1

3) Explain why passive immunization is not effective in producing long-term immunity.

Topic: Sec. 9.5

Bloom's: Applying/Analyzing

LO: 9.5b

GLO: G1