Ch.17 Test Bank Answers Defects of Plasma Clotting Factors - Test Bank | Hematology in Practice 3e by Betty Ciesla by Betty Ciesla. DOCX document preview.

Ch.17 Test Bank Answers Defects of Plasma Clotting Factors

Chapter 17. Defects of Plasma Clotting Factors

Multiple Choice

1. The following laboratory results have been obtained for a 40-year-old woman with infrequent bleeding: PT = 20 seconds (reference range is 11 to 15 seconds), APTT = 50 seconds (reference range is 22 to 40 seconds). What factor deficiency is most likely?

A. VII

B. VIII

C. X

D. XIII

L.O. 17.1

2. Which of the following is the most prevalent inherited bleeding disorder?

A. Hemophilia A

B. Hemophilia B

C. Factor VII deficiency

D. von Willebrand Disease

L.O. 17.3

3. A man with hemophilia A and an unaffected female can produce a:

A. Female carrier

B. Male carrier

C. Male with hemophilia A

D. Normal female

L.O. 17.3

4. Patients with hemophilia A or B have abnormal results in which coagulation assay?

A. APTT

B. PT

C. Fibrinogen assay

D. Platelet count

L.O. 17.5

5. A patient with 8% factor VIII activity has which form of hemophilia?

A. Severe

B. Moderate

C. Mild

D. Asymptomatic

L.O. 17.5

6. Factor assays measure the percentage of activity of a given factor by mixing the patient’s plasma with:

A. Normal plasma

B. Adsorbed plasma

C. Factor-deficient plasma

D. Factor-specific plasma

L.O. 17.5

7. Factor VIII is also known as which?

A. X factor

B. Plasminogen

C. Christmas factor

D. Antihemophilic globulin

L.O. 17.2

8. Long-term antibiotic therapy is a cause of bleeding because it disrupts:

A. Vitamin K synthesis

B. Contact activation

C. Platelet aggregation

D. Fibrinolytic activity

L.O. 17.4

9. Which of the following is the most useful in differentiating hemophilia A from hemophilia B?

A. A familial pattern of inheritance

B. Patient’s history

C. Activated partial thromboplastin time

D. Factor assays

L.O. 17.5

10. The treatment of choice for hemophilia A individuals is:

A. Cryoprecipitate

B. Recombinant factor VIII

C. Prothrombin complex

D. DDAVP

L.O. 17.6

11. The only clotting factor not synthesized exclusively by the liver is factor:

A. V

B. VII

C. VIII

D. IX

L.O. 17.1

12. Clotting factors must be present at a minimum of which percentage for hemostasis to be achieved?

A. 20%

B. 30%

C. 50%

D. 75%

L.O. 17.5

13. Which of the following assays will be abnormal with hemophilia A?

A. Platelet count

B. Bleeding time

C. PT

D. aPTT

L.O. 17.5

14. Christmas disease is another name for:

A. Hemophilia A

B. Hemophilia B

C. von Willebrand’s disease

D. Factor VII deficiency

L.O. 17.3

15. Treatment of patients with factor II, VII, or X deficiency consists of:

A. Administration of prothrombin complex concentrate

B. Administration of cryoprecipitate

C. Administration of FFP

D. Administration of whole blood

L.O. 17.7

16. Keloid scar formation is most commonly associated with:

A. Factor VIII deficiency

B. Factor IX deficiency

C. Factor XII deficiency

D. Factor XIII deficiency

L.O. 17.7

18. All of the following may lead to deficiencies of clotting factors except:

A. Renal disease

B. Liver disease

C. Autoimmune disease

D. Cardiovascular disease

L.O. 17.8

19. Which of the following is not a vitamin K–dependent factor?

A. Factor VIII

B. Factor II

C. Factor VII

D. Factor IX

L.O. 17.4

20. What is a new treatment alternative for hemophilia patients?

A. Recombinant factor VIII

B. Fresh frozen plasma

C. Gene therapy

D. Cryoprecipitate

L.O. 17.6

Document Information

Document Type:
DOCX
Chapter Number:
17
Created Date:
Aug 21, 2025
Chapter Name:
Chapter 17 Defects of Plasma Clotting Factors
Author:
Betty Ciesla

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