Test Bank Chapter 29 Epidemiology Of Urinary Bladder Cancer - Test Bank | Epidemiology of Chronic Disease 2e by Harris by Randall E. Harris. DOCX document preview.
Chapter 29. Epidemiology of Urinary Bladder Cancer
TEST BANK
True/False Questions
- During 2018, 549,393 new cases were diagnosed in the world population, and 199,922 people died from bladder cancer.
- Bladder cancer develops about 3-4 times more frequently in women than men.
- Rates of bladder cancer are highest in African nations and Eastern Mediterranean regions, particularly Egypt, where squamous cell bladder cancer arises due to chronic infection by the parasitic worm, Schistosoma haematobium.
- Rates of transitional cell carcinoma of the bladder urothelium are highest in Western Europe and other countries where the prevalence of smoking is high, particularly among men.
- The dominant risk factor for transitional cell urinary bladder cancer is cigarette smoking, which accounts for about two thirds of new cases in men and one third of new cases in women.
- Urinary bladder carcinogenesis associated with smoking is primarily the result of aromatic amines and arylamines present in cigarette smoke that reach the bladder mucosa.
- The analgesic medication, phenacetin, was once widely used in European nations until the drug was found to cause cancers of the renal pelvis and urinary bladder.
- Arsenic-contaminated drinking water by the population residing in Northern Chile was found to increase the risk of bladder cancer and lung cancer in a 50-year longitudinal study.
- Individuals who smoke and carry the NAT2 slow-acetylation mutation are at higher risk of developing bladder cancer than those without the mutation.
- African Americans living in the United States have higher rates of bladder cancer than Caucasian Americans.
Multiple Choice Questions
- What histological cell type of bladder cancer is caused by chronic schistosomiasis?
- Adenocarcinoma
- Transitional cell carcinoma
- Squamous cell carcinoma
- Sarcoma
- What histological cell type of bladder cancer is caused by chronic cigarette smoking?
- Adenocarcinoma
- Transitional cell carcinoma
- Squamous cell carcinoma
- Sarcoma
- What US subgroup has the highest risk of developing bladder cancer?
- Caucasian Americans
- African Americans
- Hispanic Americans
- Asian Americans
- Strategies for the prevention of bladder cancer include all of the following except:
- drinking 8-10 glasses of water per day.
- abstinence from tobacco use.
- avoidance of exposure to azo-dyes.
- abstinence from all alcoholic beverages.
- Which of the following analgesic drugs is carcinogenic in the urinary bladder?
- Aspirin
- Ibuprofen
- Acetaminophen
- Phenacetin
- A genetic polymorphism of what gene causes slow acetylation of arylamines from tobacco smoke that increases the risk of bladder cancer?
- BRCA1
- BRCA2
- NAT2
- GSTM1
Essay Questions
- Briefly characterize the global epidemiology of urinary bladder cancer.
- Characterize and discuss the two major histologic cell types of bladder cancer.
- Discuss the pathogenesis of squamous cell carcinoma of the bladder.
- Discuss the pathogenesis of transitional cell carcinoma of the bladder.
- How do genetic polymorphisms of the NAT2 gene affect the incidence rates of bladder cancer in African Americans versus Caucasian Americans?
- Discuss findings of the 50-year longitudinal study of bladder cancer in northern Chile.
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Connected Book
Test Bank | Epidemiology of Chronic Disease 2e by Harris
By Randall E. Harris
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