Test Bank – Ch5 Non-Mendelian Inheritance | 7e

View Product website:

https://selldocx.com/docx/test-bank-ch5-non-mendelian-inheritance-7e-1294

Student name:__________

1) In which of the following organisms does an X chromosome not get inactivated? Select all that apply.

A) Placental mammals
B) Drosophila
C) C. elegans
D) Marsupials

2) If a lethal allele is found on an X chromosome, in which organisms is it predicted that there will be a distorted ratio (not 1:1) of males to females in adults if a heterozygous female is mated to a normal male? Select all that apply.

A) Drosophila
B) Humans
C) Caenorhabitis
D) Mice

3) Which of the following is primarily responsible for the maternal effect as seen in snail shell coiling?

A) Sperm cells
B) Oocytes
C) Nurse cells
D) Placenta

4) In snail shell coiling, which of the following is responsible for the phenotype of the offspring?

A) Mother's phenotype
B) Father's phenotype
C) Mother's genotype
D) Father's genotype

5) Who originally identified a highly condensed structure in the interphase of nuclei?

A) Lyon
B) Barr
C) Ohno
D) Morgan

6) In the Igf2 gene, which allele is expressed?

A) Paternal
B) Maternal
C) Both maternal and paternal
D) Neither allele is expressed

7) Which nucleotide modification occurs in imprinting a gene?

A) Acetylation
B) Nitration
C) Phosphorylation
D) Methylation

8) Which diseases are associated with imprinting?

A) Angelman Syndrome
B) LHON
C) Alzheimer's Disease
D) All of these choices are are correct.

9) In which cells do erasure and re-establishment of nucleotide imprinting modifictions typically not occur?

A) Nurse cells
B) Sperm cells
C) Oocytes
D) Somatic cells

10) Where is extranuclear DNA located in mammalian cells?

A) Endoplasmic reticulum
B) Mitochondria
C) Ribosome
D) Plasma membrane

11) What type of inheritance is observed with extranuclear DNA?

A) Mendelian inheritance
B) Sex-linked inheritance
C) Paternal inheritance
D) Maternal inheritance
E) Maternal effect

12) What is a disease associated with extra nuclear inheritance?

A) Angelman Syndrome
B) Prader-Willi Syndrome
C) LHON
D) Muscular Dystrophy

13) What is thought to be the origin of mitochondria and chloroplasts?

A) Cyanobacteria for mitochondria, purple bacteria for chloroplasts
B) Purple bacteria for mitochondria, fungi for chloroplasts
C) Purple bacteria for mitochondria, cyanobacteria for chloroplasts
D) Algae for mitochondria, cyanobacteria for chloroplasts

14) Who is largely responsible for proposing the endosymbiosis theory?

A) Schimper, Wallin, Margulis
B) Lyon, Margulis, Schimper
C) Schimper, Wallin, Barr
D) Barr, Lyon, Margulis

15) In which type of inheritance does a change in phenotype of the offspring not rely on a change in the DNA sequence?

A) Maternal inheritance
B) Epigenetic inheritance
C) Maternal effect
D) Paternal inheritance

16) How many Barr bodies would an individual with a XXY genotype possess?

A) 0
B) 1
C) 2
D) None of these choices are correct.

17) The coat color of calico cats is a result of __________.

A) maternalinheritance
B) X-inactivation
C) imprinting
D) extranuclearinheritance

18) The Lyon hypothesis attempts to explain the molecular mechanism of __________.

A) X-inactivation
B) genomicimprinting
C) maternalinheritance
D) extranuclearinheritance

19) Monoallelic expression is associated with which of the following?

A) X-inactivation
B) Genomic imprinting
C) Maternal inheritance
D) Extranuclear inheritance

20) Which of the following is false regarding human mtDNA?

A) It is around 17,000 bp in length.
B) It is a linear chromosome.
C) Multiple copies exist in each mitochondria.
D) It mostly contains rRNA and tRNA genes, and genes for mitochondrial function.

21) Which of the following categories of genes is typically NOT encoded in cpDNA?

A) Genes encoding rRNA.
B) Genes encoding tRNA.
C) Genes for photosynthetic pathway enzymes.
D) Genes encoding nuclear proteins.

22) The inheritance of leaf pigmentation in the four-o'clock plant Mirabilis jalapa is an example of __________.

A) maternaleffect
B) maternalinheritance
C) epigeneticinheritance
D) imprinting

23) In maternal effect, the __________ of the mother determines the __________ of the offspring.

A) phenotype; genotype
B) genotype; phenotype
C) rRNA; tRNA
D) imprinting; genotype

24) A modification that occurs to a nuclear gene that alters gene expression without modifying the DNA sequence is called __________ inheritance.

A) extranuclear
B) cytoplasmic
C) maternal effect
D) epigenetic
E) nuclear

25) Dosage compensation offsets the problems associated with differences in the number of __________ chromosomes in many species.

A) cytoplasmic
B) autosome
C) sex
D) extranuclear
E) mitochondrial

26) The inheritance patterns of genetic material that is not contained in the nucleus of the cell is called __________.

A) extranuclear inheritance
B) maternaleffect
C) imprinting
D) nuclear
E) epigenetic

27) mtDNA stands for __________ and cpDNA stands for __________.

A) extranuclear DNA; cytoplasmic DNA
B) maternal DNA; paternal DNA
C) marked DNA; copied DNA
D) nuclear; cytoplasmic
E) mitochondrial DNA; chloroplast DNA

28) Heteroplasmy is associated with inheritance patterns involving __________.

A) nuclear
B) paternal DNA
C) chloroplasts
D) ribosomes
E) imprinted

29) If the sperm cell contributes mitochondria to the oocyte, it is called __________.

A) paternalleakage
B) maternalleakage
C) paternalinheritance
D) mitochondria
E) imprinting

30) A symbiotic relationship where one organism lives inside another species is called __________.

A) cytoplasmicinheritance
B) heteroplasmy
C) paternalleakage
D) endosymbiosis

31) What would be the genotype of the mother of a female snail that has a Dd genotype and a shell with a left hand twist?

A) dd
B) DD
C) Dd
D) Cannot tell since the shell twist phenotype of any offspring depends on the genotype of the father as well as the mother.

32) What is the geneotype of the father for a snail that has the genotype Dd and has a left hand twist shell?

A) dd
B) Dd
C) DD
D) It cannot be determined.

33) If a snail that has a right hand twist and is DD is mated to a snail that has a left hand twist and is dd what is the expected ratio of progeny?

A) 3 left hand to 1 right hand
B) 3 right hand to 1 left hand
C) It depends on which snail is female and which is male.
D) 1 left hand to 1 right hand

34) What is the phenotype of the father of a woman who has Prader-Willi syndrome?

A) The father has Prader-Willi syndrome.
B) The father could have two normal copies of chromosome 15 and therefore wouldn't have either syndrome.
C) The father has either Prader-Willi or Angelman syndrome depending on the parent from which he inherited his deleted chromosome 15.
D) The father has Angleman syndrome.

35) A man with Prader-Willi syndrome has children with a woman that has Angelman syndrome what is the expected ratio of progeny?

A) 1 Prader-Willi : 1 Angelman : 2 normal
B) 1 Prader-Willi : 1 Angelman : 1 normal : 1 both Angelman and Prader-Willi
C) 1 normal : 1 both Angelman and Prader-Willi
D) 1 Prader-Willi (all males) : 1 Angelman (all female)

36) Yeast can reproduce either by mitosis or they undergo a mating process whereby two haploid cells fuse to make a diploid cell and mix their cytoplasms before they undergo meiosis to form spores. There are several yeast strains that are known as petites that grow more slowly than their normal counterparts and they have mitochondria that perform more poorly than normal mitochondria. Some petite strains and normal yeast cell matings result in the haploid progeny being all normal and some result in their being a 1:1 ratio of normal to petite haploid progeny. What is the explanation for this?

A) Petite mutations all arise in mitochondrial genes.
B) Petite mutations all arise from mutations in nuclear genes.
C) Some petite mutations occur in nuclear genes and some occur in mitochondrial genes.
D) Petite progeny all arise from random mutations.

37) If a man who has a syndrome has children with a woman who is normal and the children have a 1syndromic : 1 normal ratio what can be concluded about the mode of inheritance? Remember that most syndromes are quite rare so it can be assumed that those with the syndrome are heterozygotes if the gene is located on a nuclear chromosome.

A) It is extranuclear.
B) It is maternal effect.
C) It is imprinting.
D) It is codominance.

38) Which of the following is an example of epigenetic inheritance?

A) Expression of the Igf-2 gene based on methylation of the ICR and DMR regions
B) Inheritance of flower color as studied by Mendel
C) Leaf coloration based on mitochondrial inheritance
D) Snail shell twist patterns