Epidemiology Of Multiple Sclerosis Chapter 50 Exam Questions - Test Bank | Epidemiology of Chronic Disease 2e by Harris by Randall E. Harris. DOCX document preview.

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Epidemiology Of Multiple Sclerosis Chapter 50 Exam Questions

Chapter 50. Epidemiology of Multiple Sclerosis

TEST BANK

True/False Questions

  1. Multiple Sclerosis is an autoimmune inflammatory disease in which the myelin sheaths surrounding the axons of neurons (nerve cells) are damaged or destroyed, leading to demyelination and scarring as well as a broad spectrum of signs and symptoms.
  2. Since almost any neurological symptom can appear in patients with multiple sclerosis, other conditions must be ruled out in reaching the diagnosis.
  3. Worldwide, there are more than 2 million people living with multiple sclerosis.
  4. The annual prevalence of multiple sclerosis ranges from 1 to 176 per 100,000 among populations with a median value of about 30 per 100,000.
  5. The annual incidence of multiple sclerosis ranges from 1 to 290 per million among populations with a median value of 25 per million.
  6. Life expectancy in patients with multiple sclerosis is reduced by about 10 years compared to the general population.
  7. Suicide rates in cohorts of patients with multiple sclerosis are similar to rates in corresponding general populations.
  8. Multiple sclerosis is characterized by disruptions in the blood-brain barrier, inflammatory gliosis, and demyelination and death of neurons.
  9. The concordance of multiple sclerosis in dizygotic twins is similar to that in monozygotic twins.
  10. Vitamin D supplementation may have chemopreventive/therapeutic benefit against development/progression of multiple sclerosis.

Multiple Choice Questions

  1. Approximately how many people suffer from multiple sclerosis in the world population?
    1. 1 million
    2. 2 million
    3. 3 million
    4. 4 million
  2. The median annual prevalence of multiple sclerosis is approximately:
    1. 10 cases per million.
    2. 25 cases per million.
    3. 30 cases per 100,000.
    4. 100 cases per 100,000.
  3. The median annual incidence rate of multiple sclerosis is approximately:
    1. 10 cases per million.
    2. 25 cases per million.
    3. 30 cases per 100,000.
    4. 100 cases per 100,000.
  4. Compared to the general population, the average life expectancy among patients with multiple sclerosis is decreased by about:
    1. 5 years.
    2. 10 years.
    3. 15 years.
    4. 20 years.
  5. Compared to the general population, what is the risk of suicide among patients with multiple sclerosis?
    1. Suicide risks are similar.
    2. Suicide risk is increased by about 50%.
    3. Suicide risk is increased nearly 2-fold.
    4. Suicide risk is increased 10-fold.
  6. Risk factors for multiple sclerosis include all of the following except:
    1. genetic predisposition.
    2. active EBV infection.
    3. Borreliosis.
    4. living near the equator.
  7. The concordance of multiple sclerosis among monozygous twins is approximately:
    1. 10%.
    2. 20%.
    3. 50%.
    4. 100%.
  8. Which of the following factors has been found to have chemopreventive effects against the development of multiple sclerosis?
    1. Vaccination against influenza
    2. Dietary supplementation with folic acid
    3. Dietary supplementation with Vitamin D
    4. Increasing intake of omega-3 fatty acids

Essay Questions

  1. Define multiple sclerosis and discuss criteria for its diagnosis.

  1. Characterize the global distribution of multiple sclerosis.

  1. Describe characteristic pathologic features of multiple sclerosis.

  1. Characterize the case fatality and risk of suicide among patients with multiple sclerosis.

  1. Discuss infectious agents that have been found in association with the development of multiple sclerosis.

  1. Discuss findings of studies of vitamin D and multiple sclerosis.

  1. Discuss the known risk factors for multiple sclerosis.

  1. Discuss prospects for improving the treatment of multiple sclerosis.

Document Information

Document Type:
DOCX
Chapter Number:
50
Created Date:
Aug 21, 2025
Chapter Name:
Chapter 50 Epidemiology Of Multiple Sclerosis
Author:
Randall E. Harris

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