Chapter 19 Full Test Bank Epidemiology Of Pancreatic Cancer - Test Bank | Epidemiology of Chronic Disease 2e by Harris by Randall E. Harris. DOCX document preview.
Chapter 19. Epidemiology of Pancreatic Cancer
TEST BANK
True/False Questions
- During the decade, 2008-2018, the annual number of cases of pancreatic cancer in the world population increased by 65%, and the number of deaths from this malignancy increased by 62%.
- Most pancreatic tumors arise from the Islets of Langerhans (endocrine cells that secrete insulin, glucagon, and other polypeptide hormones).
- Most pancreatic tumors arise from the epithelial lining of the exocrine pancreas (the ducts that secrete powerful digestive enzymes).
- Tobacco addiction and chronic alcohol consumption are independent risk factors for the development of pancreatic cancer.
- Higher rates of pancreatic cancer have been found in association with increased dietary intake of saturated fats from animal and dairy sources.
- Higher rates of pancreatic cancer have been found in association with increased dietary intake of omega-3 fatty acids from fish oil and olive oil.
- Chronic pancreatitis predisposes to the development of pancreatic cancer.
- The main cause of chronic pancreatitis is tobacco smoking.
- Germ line mutations clearly cause more pancreatic cancers than somatic mutations.
- Type 2 diabetes is associated with the development of pancreatic cancer, although studies of these conditions may be influenced by “reverse causality bias.”
Multiple Choice Questions
- What is the percentage of pancreatic cancers that arise in the exocrine portion of the gland?
- 80%
- 90%
- 95%
- 99%
- Approximately 99% of malignant pancreatic tumors are:
- squamous cell carcinomas.
- adenocarcinomas.
- sarcomas.
- lymphomas.
- The risk of pancreatic cancer is increased by:
- high intake of omega-3 fatty acids.
- high intake of omega-6 fatty acids.
- low intake of saturated fats.
- high intake of saturated fats.
- a and c are correct.
- b and d are correct.
- Significant causes of chronic pancreatitis include all of the following except:
- chronic alcohol abuse.
- chronic cholelithiasis.
- autoimmune disease.
- cigarette smoking.
- Cystic fibrosis increases the risk of pancreatic cancer by approximately:
- two-fold.
- five-fold.
- ten-fold.
- twenty-fold.
- Somatic mutations of what gene are found in up to 90% of pancreatic tumors?
- BRCA-1
- BRCA-2
- CFTR
- K-RAS
- What type of bias may influence the association of type 2 diabetes and pancreatic cancer?
- Berkson’s bias
- Differential selection bias
- Reverse causality bias
- Protopathic bias
- Over-expression of what inducible gene is found in a high percentage of pancreatic tumors?
- COX-1
- COX-2
- BRCA-1
- BRCA-2
Essay Questions
- Briefly describe the global burden of pancreatic cancer.
- Describe the anatomic structure of the pancreas and the cellular origin of most pancreatic tumors.
- Discuss the known risk factors for pancreatic cancer.
- Define reverse causality bias and discuss its influence on the association of type 2 diabetes and pancreatic cancer.
- Discuss genetic factors that increase the risk of developing pancreatic cancer.
- Discuss potential strategies for the prevention of pancreatic cancer.
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Test Bank | Epidemiology of Chronic Disease 2e by Harris
By Randall E. Harris
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