Final Test Bank Chapter 18 Epidemiology Of Colon Cancer - Test Bank | Epidemiology of Chronic Disease 2e by Harris by Randall E. Harris. DOCX document preview.
Chapter 18. Epidemiology of Colon Cancer
TEST BANK
True/False Questions
- In 2018, colorectal (large bowel) cancer was diagnosed in 1,800,977 individuals and caused more than 861,663 deaths in the world population.
- Colorectal cancer is the third leading cause of cancer deaths among men (464,606 deaths in 2018) and the fourth leading cause of cancer deaths among women (387,057 deaths in 2018).
- Colorectal cancer is much more common in developing countries than developed countries.
- Colon cancer most often arises in the descending portion of the colon.
- Higher rates of colon cancer have been found in association with increased dietary intake of omega-6 fatty acids from beef, corn oil, or lard in the diet.
- Higher rates of colon cancer have been found in association with increased dietary intake of omega-3 fatty acids from fish oil and olive oil.
- Denis Burkitt recommended intake of 40 grams of fiber daily for the prevention of colorectal cancer.
- Chronic exposure to tobacco and alcohol do not increase the risk of colon cancer.
- Colon cancer rates are highest near the equator.
- Hyperinsulinemia is a risk factor for the development of colon cancer.
Multiple Choice Questions
- What percentage of colon cancers arise in the descending colon?
- 35%
- 45%
- 55%
- 65%
- Approximately 95% of malignant colon tumors are:
- squamous cell carcinomas.
- adenocarcinomas.
- sarcomas.
- lymphomas.
- The risk of colon cancer is inversely related to the intake of:
- high intake of Omega-3 fatty acids.
- high intake of Omega-6 fatty acids.
- high intake of insoluble dietary fiber.
- low intake of insoluble dietary fiber.
- a and c are correct.
- b and d are correct.
- Rates of colon cancer show what geographical gradient?
- Rates increase with distance from the equator.
- Rates decrease with distance from the equator.
- Rates are higher in the northern hemisphere.
- Rates do not show any geographical pattern.
- Approximately what percentage of colon cancer cases arise due to heritable germline mutations?
- < 10%
- 10-20%
- 20-30%
- 30-40%
- What drugs consistently show chemopreventive effects against colon cancer development?
- Statins
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Anti-hypertensive medications
- Antidepressants
- Hormone replacement therapy (HRT) has been found to increase the risk of all of the following forms of cancer except:
- breast cancer.
- endometrial cancer.
- colon cancer.
- None of the above is correct.
- All of the following factors may have contributed to the decline in colon cancer mortality in the United States during the past several decades except:
- the increasing use of colonoscopy for screening.
- improvements in therapy.
- the increasing intake of fish oil.
- the declining use of NSAIDs.
Essay Questions
- Describe the global burden of colon cancer.
- Describe the pathogenesis and anatomic distribution of colorectal cancer.
- Discuss lifestyle risk factors that increase the risk of colon cancer.
- Discuss Burkitt’s “High Fat Low Fiber” theory of colon cancer.
- Discuss genetic factors that increase the risk of developing colon cancer.
- Discuss insulin and insulin like growth factor (IGF) in the development of colon cancer.
- Discuss evidence for a role of vitamin D deficiency in the development of colon cancer.
- Discuss recent trends in colon cancer mortality in the USA and other developed nations including possible reasons for these trends.
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Test Bank | Epidemiology of Chronic Disease 2e by Harris
By Randall E. Harris
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