Memory Formation Early Stages Ch.10 Verified Test Bank 3e - Neurobiology Learning 3e | Test Bank Rudy by Jerry W. Rudy. DOCX document preview.
Chapter 10: Memory Formation: Early Stages
Test Bank
Type: true-false
Title: Chapter 10 - Question 1
1. The formation of a memory trace begins when a behavioral experience activates a neuronal ensemble that represents the experience.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 2
2. An important step in the generation of a memory is the release of glutamate onto dendritic spines.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 3
3. Morris used genetically engineered mice in the first study that investigated the role of NMDA receptors in memory formation.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 4
4. Morris used a pharmacological treatment to study the role of NMDA receptors in memory formation.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 5
5. GluN1 subunits are not required to form functional NMDA receptors.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 6
6. GluN1 subunits are necessary to form functional NMDA receptors.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 7
7. The CA1KO mouse was able to display LTP in the CA1 regions but not in the dentate gyrus.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 8
8. The CA1KO mouse was able to display LTP in the dentate gyrus region but not in the CA1.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 9
9. Memory formation can take place without the contribution of NMDA receptors.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 10
10. Ampakines are neither agonists nor antagonists.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 11
11. Ampakines are an example of a receptor modulator.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 12
12. A behavioral experience that produces a memory is likely to result in more phosphorylated cofilin and more autophosphorylated CaMKII.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 13
13. NMDA receptors are required for both the acquisition and the retrieval of memories.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 14
14. The Doogie mouse was engineered to overexpress GluN2A receptors.
a. True
b. False.
Type: true-false
Title: Chapter 10 - Question 15
15. The Doogie mouse was engineered to overexpress GluN2B receptors.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 16
16. GluN1-GluN2B to GLuN1-GLuN2A receptors ratio increases during development.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 17
17. GluN1–GluN2A receptor complexes influx more calcium than GluN1–GluN2B receptor complexes.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 18
18. Remembering the plot of a book you read a few months ago is an example of working memory.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 19
19. AMPA receptors are needed only for memory acquisition, but NMDA receptors are required for both acquisition and retrieval.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 20
20. Working memory cannot be studied in animals because they cannot communicate what problems they are trying to solve.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 21
21. An enduring LTP can be established independent of any contribution from GluA1 receptors, but it requires GluA2 AMPA receptors.
a. True
b. False
Type: true-false
Title: Chapter 10 - Question 22
22. When glutamate and ampakines both bind to the AMPA receptor, the channel stays open longer.
a. True
b. False
Type: essay/short answer question
Title: Chapter 10 - Question 23
23. Morris was the first to find a possible role for NMDA receptors in memory formation. What was his essentially methodology?
Type: essay/short answer question
Title: Chapter 10 - Question 24
24. Describe the composition of the NMDA receptor.
Type: essay/short answer question
Title: Chapter 10 - Question 25
25. How did Tonegawa’s laboratory discover a role for the GluN1 receptor?
Type: essay/short answer question
Title: Chapter 10 - Question 26
26. Explain why it is possible to induce LTP in the dentate gyrus of the CA1KO mouse, but not in the CA1 region of the brain. How does this affect the mouse’s performance in the place-learning task?
Type: essay/short answer question
Title: Chapter 10 - Question 27
27. Why would infant mice display stronger LTP than older mice?
Type: essay/short answer question
Title: Chapter 10 - Question 28
28. Roberto Malinow’s laboratory (Rumpel et al., 2006) used two strategies to prove that fear conditioning drives AMPA receptors into amygdala neuron synapses. What were they?
Type: essay/short answer question
Title: Chapter 10 - Question 29
29. In Malinow’s AMPA receptor trafficking experiment, what was the difference between the rats in the paired condition and the rats in the unpaired condition?
Type: essay/short answer question
Title: Chapter 10 - Question 30
30. What are ampakines?
Type: essay/short answer question
Title: Chapter 10 - Question 31
31. Is it reasonable to expect that behavioral experiences that produce memories would engage the LIMK signaling pathway? Why?
Type: essay/short answer question
Title: Chapter 10 - Question 32
32. Provide an example of working memory.
Type: essay/short answer question
Title: Chapter 10 - Question 33
33. Describe how the radial arm maze can be used to study both working and reference memory.