3e Test Questions & Answers Chapter.11 Memory Consolidation - Neurobiology Learning 3e | Test Bank Rudy by Jerry W. Rudy. DOCX document preview.
Chapter 11: Memory Consolidation
Test Bank
Type: true-false
Title: Chapter 11 - Question 1
1. Short-term memories are more vulnerable to disruption than long-term memories.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 2
2. The decay rate for long-term memories is more rapid than the decay rate for short-term memories.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 3
3. If a molecule is critical for long-term memory, it should also be critical for short-term memory.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 4
4. To determine the role of a molecule in memory the experiment should use at least two retention intervals.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 5
5. A memory may be considered consolidated when it is no longer vulnerable to transcription and translation inhibitors.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 6
6. Blocking protein synthesis interferes with the formation of short-term memories.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 7
7. Alberini’s laboratory found that inhibiting protein synthesis (with anisomycin) a few minutes after training did not interfere with retention two days after training but did prevent retention seven and nine days later.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 8
8. Rapamycin administer prior to training interfered with retention one hour later.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 9
9. Rapamycin administer prior to training interfered with retention two and seven days later.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 10
10. That rapamycin administers just before training interfered with retention two and seven days later indicates that the mTOR pathway is critically for at least two ways of protein synthesis.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 11
11. Disrupting either the mTORC1 or the mTORC2 complex will impair the development of long-term memory but have no influence on the formation of short-term memory.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 12
12. The mTORC2 complex regulates protein synthesis but the mTORC1 complex regulates actin polymerization.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 13
13. The mTORC2 complex regulates actin polymerization but the mTORC1 complex regulates protein synthesis.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 14
14. The TOP protein 4E-BP normally interferes with the initiation of local protein synthesis.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 15
15. If the first wave of BDNF protein synthesis is blocked retention at both the one- and seven-day interval will be impaired.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 16
16. The BDNF-TrkB pathway is critical to two waves of protein synthesis.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 17
17. The second wave of protein synthesis depends on genomic signaling initiated by the BDNF-TrkB pathway.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 18
18. The TrkB receptor is activated by the first messenger glutamate.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 19
19. C/EBPβ is targeted by CaMKII for transcription.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 20
20. C/EBPβ is targeted by CREB for transcription.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 21
21. C/EBPβ is a transcription factor.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 22
22. C/EBPβ is critical to the first wave of protein synthesis.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 23
23. C/EBPβ is critical to the second wave of protein synthesis.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 24
24. Inhibiting protein synthesis should effect short-term memory.
a. True
b. False
25 The mTORC1 complex is important to local protein synthesis.
a. True
b. False
Type: true-false
Title: Chapter 11 - Question 26
26. If C/EBPβ is inhibited, BDNF will be transcribed
a. True
b. False
Type: essay/short answer question
Title: Chapter 11 - Question 27
27. What is the key independent variable manipulated to determine if a molecule is selectively involved in LTM but not STM?
Type: essay/short answer question
Title: Chapter 11 - Question 28
28. What is the retention interval?
Type: essay/short answer question
Title: Chapter 11 - Question 29
29. A drug inhibits molecule X, and it impaired performance at the long, 24-hour retention interval but had no effect on performance at the short, 1-hour retention interval. What can be said about the contribution of molecule X to memory?
Type: essay/short answer question
Title: Chapter 11 - Question 30
30. How did John Guzowski examine the importance of CREB for memory retention?
Type: essay/short answer question
Title: Chapter 11 - Question 31
31. What were the results and implications of systematically injecting the protein-synthesis inhibitor anisomycin prior to fear conditioning?
Type: essay/short answer question
Title: Chapter 11 - Question 32
32. Why would one vary the interval separating training and the administration of a protein synthesis inhibitor such as anisomycin?
Type: essay/short answer question
Title: Chapter 11 - Question 33
33. Anisomycin administered just prior to training prevents retention at two-, seven-, and nine-day intervals. But, if anisomycin is administered just a few minutes following training, it only impairs retention at the seven- and nine-day intervals. What does this collection of findings imply?
Type: essay/short answer question
Title: Chapter 11 - Question 34
34. What is the role of C/EBPβ in the autoregulatory loop?
Type: essay/short answer question
Title: Chapter 11 - Question 35
35. What is the role of BDNF in the autoregulatory loop?
Type: essay/short answer question
Title: Chapter 11 - Question 36
36. What are the differences between mTORC1 and mTORC2?
Type: essay/short answer question
Title: Chapter 11 - Question 37
37. What is the evidence that proteins translated in response to the mTORC1 signaling are important for the consolidation of long-term memory but not for producing a short-term memory?
Type: essay/short answer question
Title: Chapter 11 - Question 38
38. Why is the rictor KO mouse useful?
Type: essay/short answer question
Title: Chapter 11 - Question 39
39. What is the importance of the two distinct peak levels of BDNF expression?
Type: essay/short answer question
Title: Chapter 11 - Question 40
40. Describe two sources of evidence that BDNF is important for memory consolidation.
Type: essay/short answer question
Title: Chapter 11 - Question 41
41. How might sleep contribute to consolidation?
Type: essay/short answer question
Title: Chapter 11 - Question 42
42. What is the evidence that the UPS is involved in memory consolidation?
Document Information
Connected Book
Explore recommendations drawn directly from what you're reading
Chapter 9 Making Memories Conceptual Issues And Methodologies
DOCX Ch. 9
Chapter 10 Memory Formation Early Stages
DOCX Ch. 10
Chapter 11 Memory Consolidation
DOCX Ch. 11 Current
Chapter 12 Memory Modulation Systems
DOCX Ch. 12
Chapter 13 The Yin And Yang Of Memory Forgetting Versus Maintenance
DOCX Ch. 13