Exam Questions Ch2 From Hematopoiesis to the Complete Blood

Chapter 2. From Hematopoiesis to the Complete Blood Count

Multiple Choice

1. What is the average M:E ratio for normal adult bone marrow?

A. 1:3

B. 4:1

C. 1:4

D. 6:1

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2. The key organs involved in extramedullary hematopoiesis include the:

A. Kidney and thymus

B. Lymph nodes and heart

C. Liver and spleen

D. Kidney and liver

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3. Which of these assays is the best test to assess the bone marrow’s response to anemic stress?

A. Hemoglobin value

B. MCV value

C. Reticulocyte count

D. Hematocrit

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4. All of the following splenic functions are related to hematopoiesis, except:

A. Production of opsonizing antibodies

B. Production of WBCS, if necessary

C. Filtering out of old or deformed cells

D. Storage of platelets and granulocytes

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5. Which of the following is a primary site for hematopoiesis in a fetus of 4 to 5 months’ gestation?

A. Yolk sac

B. Spleen

C. Distal long bones

D. Axial skeleton

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6. A patient with the following values—RBC = 4.01 × 10¹²/L, Hgb = 12.5 g/dL, and Hct = 37.2%—will most likely have which of the following RBC indices?

A. MCV = 92.8 fL, MCH = 31.2 pg, MCHC = 33.6%

B. MCV = 92.8 fL, MCH = 33.6 pg, MCHC = 31.2%

C. MCV = 107.8 fL, MCH = 32.1 pg, MCHC = 33.6%

D. MCV = 132.2 fL, MCH = 32.1 pg, MCHC = 33.5%

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7. The hormone responsible for red blood cell development in the bone marrow is:

A. Thyroxin

B. Insulin

C. Leukopoietin

D. Erythropoietin

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8. Which of the following sites is the most preferable for bone marrow aspiration and biopsy in adults?

A. Sternum

B. Iliac crest

C. Fibula

D. Vertebra

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9. A patient’s hemoglobin is 12.3 g/dL. On the peripheral smear, the red cells appear normochromic and normocytic. The hematocrit value that correlates with these data is:

A. 34%

B. 37%

C. 40%

D. 43%

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10. A Wright-stained smear of a patient’s bone marrow would effectively reveal all the following cells except:

A. Iron-containing cells

B. RBC precursor cells

C. WBC precursor cells

D. Mature WBCs

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11. Erythropoietin is produced by the:

A. Kidneys

B. Liver

C. Spleen

D. Thymus gland

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12. Bone marrow aspiration is usually required in conditions of:

A. Anemia

B. Hypoxia

C. Leukemia

D. Hepatosplenomegaly

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13. Opsonizing antibodies produced by the spleen serve to:

A. Strip the capsule from bacterial pathogens

B. Recycle erythrocyte byproducts

C. Aid in extramedullary hematopoiesis

D. Fight viral infection

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14. The spleen harbors _____ of the circulatory platelet mass.

A. one-quarter

B. one-third

C. one-half

D. three-quarters

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15. Mature red blood cells leave the bone marrow and enter the circulation via the:

A. Reticuloendothelial system

B. Osteoclasts

C. Spleen

D. Bone marrow sinuses

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16. Which of the following is a site of extramedullary hematopoiesis in an adult?

A. Spleen

B. Liver

C. Iliac crest

D. Both A and B

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17. The ______ is one of the most stable parameters in a CBC.

A. MCV

B. Hct

C. MCHC

D. MCH

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18. The CBC parameter that gives insight into the amount of anisocytosis present in a specimen is:

A. RDW

B. MCHC

C. MCV

D. Hgb

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True/False

19. The CFU-GEMM is a multipotential stem cell, capable of differentiating into a lymphoid or nonlymphoid precursor committed cell.

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20. Patients with moderate anemias (7 to 10 g/dL) may be asymptomatic.

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