Chapter 24 Acyl Substitution Reactions Complete Test Bank

Chapter 24: Carboxylic Acids and Derivatives: Nucleophilic Acyl Substitution and α-Substitution Reactions

Test Bank

Type: matching question

Title: Chapter 24 Question 01

1) Rank the following molecules, A-D, in order of their relative electrophilicity (where 1 is the most electrophilic and 4 is the least electrophilic):

Section reference: 24.1

a. 1 = Molecule B

b. 2 = Molecule D

c. 3 = Molecule C

d. 4 = Molecule A

Type: matching question

Title: Chapter 24 Question 02

2) Rank the following molecules, A-D, in order of their relative acidity (where 1 is the most acidic and 4 is the least acidic):

Section reference: 24.1

a. 1 = Molecule B

b. 2 = Molecule C

c. 3 = Molecule D

d. 4 = Molecule A

Type: multiple choice question

Title: Chapter 24 Question 03

3) For the following reaction, pick out a suitable rate profile from A-D for this transformation:

a. A

Section reference: 24.1

b. B

Section reference: 24.1

c. C

Section reference: 24.1

d. D

Section reference: 24.1

Type: multiple response question

Title: Chapter 24 Question 04

4) For the following reaction, pick out the products. Please select all that apply.

a. A

Section reference: 24.2

b. B

Section reference: 24.2

c. C

Section reference: 24.2

d. D

Section reference: 24.2

e. E

Section reference: 24.2

Type: multiple response question

Title: Chapter 24 Question 05

5) From the following reactions, A-D, pick out those which lead to the formation of ethyl acetate (ethyl ethanoate). Please select all that apply.

a. A

Section reference: 24.2

b. B

Section reference: 24.2

c. C

Section reference: 24.2

d. D

Section reference: 24.2

Type: multiple choice question

Title: Chapter 24 Question 06

6) For the following transformation, deduce whether it is an oxidation, reduction or neither:

a. Oxidation

Section reference: 24.2

b. Reduction

Section reference: 24.2

c. Neither

Section reference: 24.2

Type: matching question

Title: Chapter 24 Question 07

7) Rank the following molecules, A-D, in order of their ability to form enols (with 1 being most able and 4 the least able):

Section reference: 24.3

a. 1 = Molecule B

b. 2 = Molecule D

c. 3 = Molecule C

d. 4 = Molecule A

Type: multiple choice question

Title: Chapter 24 Question 08

8) For the following reaction, pick out the major product:

a. A

Section reference: 24.2

b. B

Section reference: 24.2

c. C

Section reference: 24.2

d. D

Section reference: 24.2

e. E

Section reference: 24.2

Type: multiple response question

Title: Chapter 24 Question 09

9) For the following reaction, pick out the product:

a. A

Section reference: 24.2

b. B

Section reference: 24.2

c. C

Section reference: 24.2

d. D

Section reference: 24.2

e. E

Section reference: 24.2

Type: multiple choice question

Title: Chapter 24 Question 10

10) For the following reaction, pick out the major product::

a. A

Section reference: 24.2

b. B

Section reference: 24.2

c. C

Section reference: 24.2

d. D

Section reference: 24.2

e. E

Section reference: 24.2

Type: multiple response question

Title: Chapter 24 Question 11

11) For the following reactions, A-D, pick out those which lead to the formation of 2-methyl-2-phenylethanol. Please select all that apply.

a. A

Section reference: 24.2

b. B

Section reference: 24.2

c. C

Section reference: 24.2

d. D

Section reference: 24.2

Type: multiple choice question

Title: Chapter 24 Question 12

12) For the following reaction, pick out the major product:

a. A

Section reference: 24.2

b. B

Section reference: 24.2

c. C

Section reference: 24.2

d. D

Section reference: 24.2

e. E

Section reference: 24.2

Type: multiple response question

Title: Chapter 24 Question 13

13) Which of the following reagents, A-E, are suitable reagents for the following transformation? Please select all that apply.

a. A

Section reference: 24.2

b. B

Section reference: 24.2

c. C

Section reference: 24.2

d. D

Section reference: 24.2

e. E

Section reference: 24.2

Type: multiple choice question

Title: Chapter 24 Question 14

14) Which of the following reagents, A-D, is a suitable reagent for the following transformation?

a. A

Section reference: 24.2

b. B

Section reference: 24.2

c. C

Section reference: 24.2

d. D

Section reference: 24.2

Type: multiple choice question

Title: Chapter 24 Question 15

15) Which of the following reagents, A-E, is a suitable reagent for the following transformation?

a. A

Section reference: 24.2, 23.2

b. B

Section reference: 24.2, 23.2

c. C

Section reference: 24.2, 23.2

d. D

Section reference: 24.2, 23.2

e. E

Section reference: 24.2, 23.2

Type: multiple choice question

Title: Chapter 24 Question 16

16) Which of the following reagents, A-E, is a suitable reagent for the following transformation?

a. A

Section reference: 24.2

b. B

Section reference: 24.2

c. C

Section reference: 24.2

d. D

Section reference: 24.2

e. E

Section reference: 24.2

Type: multiple choice question

Title: Chapter 24 Question 17

17) From the following equilibrium, pick out the approximate equilibrium constant for this process:

a. 10^-0.64

Section reference: 24.3

b. 10^-1.56

Section reference: 24.3

c. 10^-9

Section reference: 24.3

d. 10^-12

Section reference: 24.3

e. 10^-16

Section reference: 24.3

Type: matching question

Title: Chapter 24 Question 18

18) Rank the following molecules, A-D, in order of their relative acidity (where 1 is the most acidic and 4 is the least acidic):

Section reference: 24.3

a. 1 = Molecule B

b. 2 = Molecule D

c. 3 = Molecule C

d. 4 = Molecule A

Type: multiple choice question

Title: Chapter 24 Question 19

19) For the following Claisen reaction, pick out the product:

a. A

Section reference: 24.3

b. B

Section reference: 24.3

c. C

Section reference: 24.3

d. D

Section reference: 24.3

e. E

Section reference: 24.3

Type: multiple choice question

Title: Chapter 24 Question 20

20) For the following reaction, pick out the major product:

a. A

Section reference: 24.3

b. B

Section reference: 24.3

c. C

Section reference: 24.3

d. D

Section reference: 24.3

e. E

Section reference: 24.3

Type: multiple choice question

Title: Chapter 24 Question 21

21) Identify the reaction class for the following reaction:

a. Nucleophilic acyl substitution

Section reference: 24.1

b. α-substitution

Section reference: 24.1

c. carbonyl-carbonyl condensation

Section reference: 24.1

d. nucleophilic alkyl substitution

Section reference: 24.1

Type: multiple response question

Title: Chapter 24 Question 22

22) A Dieckmann reaction is an example of what type of process? Please select all that apply.

Section reference: 24.3

a. Saponification reaction

b. Claisen condensation reaction

c. An intramolecular reaction

d. S_N2 reaction

Type: multiple response question

Title: Chapter 24 Question 23

23) How can the formation of ethyl butanoate from butanoic acid and ethanol be favoured? Please select all that apply.

Section reference: 24.2

a. Add a drying agent (e.g. molecular sieves) b. Distillation (e.g. using a Dean-Stark trap) c. Lower reaction temperature (e.g. ice bath) d. Use water as a solvent

e. Use ethanol as a solvent

Type: multiple choice question

Title: Chapter 24 Question 24

24) Predict the major product of the following reaction, at room temperature.

a. A

Section reference: 24.2

b. B

Section reference: 24.2

c. C

Section reference: 24.2

d. D

Section reference: 24.2

Type: multiple choice question

Title: Chapter 24 Question 25

25) Identify the major enol of methyl 3-oxopentanoate.

a. A

Section reference: 24.3

b. B

Section reference: 24.3

c. C

Section reference: 24.3

d. D

Section reference: 24.3