Holland/Adams/Brice, Core Concepts in Pharmacology 5th Edition Test Bank
Chapter 26

Question 1

Type: MCSA

The nurse is teaching a client about body defenses. Which defenses should the nurse include in the teaching when referring to innate defenses?

1. The skin
2. The liver
3. Cell-mediated immunity
4. Immunoglobulins (Ig)

Cognitive Level: Understanding

Client Need: Physiological Integrity

Page Number: 407

Nursing/Integrated Concepts: Nursing Process: Planning

Learning Outcome: 26-1 Compare and contrast innate and adaptive body defenses.

Question 2

Type: MCSA

What is the medical term for immunity that is initiated when an antigen encounters a type of lymphocyte known as a B cell?

1. Cell-mediated
2. Cytokines
3. Humoral
4. Vaccine

Cognitive Level: Remembering

Client Need: Health Promotion and Maintenance

Page Number: 408

Nursing/Integrated Concepts: Nursing Process: Assessment

Learning Outcome: 26-2 Compare and contrast the humoral and cell-mediated immune responses.

Question 3

Type: MCSA

The nurse is caring for a client who is scheduled to receive several vaccinations. Which vaccine is a live attenuated vaccine?

1. Measles, mumps, and rubella vaccine
2. Tetanus toxoid
3. Hepatitis A vaccine
4. Influenza

Cognitive Level: Applying

Client Need: Physiological Integrity

Page Number: 409

Nursing/Integrated Concepts: Nursing Process: Implementation

Learning Outcome: 26-3 Explain the types of vaccines and how they are used to prevent illness.

Question 4

Type: MCSA

An adult client is receiving hepatitis B (Engerix-B) injections. The nurse anticipates that the client will receive these injections on which schedule?

1. The first dose at age 11 or 12 years, the second dose 2 months after the first dose, and the third dose 6 months after the first dose
2. First dose followed by a booster 6–12 months later
3. Single annual dose
4. Three doses, with the second dose 30 days after the first and the final dose 6 months after the first

Cognitive Level: Understanding

Client Need: Physiological Integrity

Page Number: 410

Nursing/Integrated Concepts: Nursing Process: Implementation

Learning Outcome: 26-3 Explain the types of vaccines and how they are used to prevent illness.

Question 5

Type: MCMA

The nurse is caring for a client who has been prescribed an interferon. What effect does the nurse anticipate this medication will have on the client? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected.

1. Anti-inflammatory action
2. Decrease the heart rate
3. Slow the spread of viral infections
4. Increase the blood pressure
5. Stabilize normal immune responses

Cognitive Level: Applying

Client Need: Physiological Integrity

Page Number: 412

Nursing/Integrated Concepts: Nursing Process: Implementation

Learning Outcome: 26-4 Identify indications for pharmacotherapy with biologic response modifiers.

Question 6

Type: MCSA

The nurse is caring for a client who underwent a kidney transplant. What medication does the nurse expect to administer?

1. Cyclosporine (Sandimmune)
2. Nabumetone (Relafen)
3. Phenytoin (Dilantin)
4. Cortisone (Cortone)

Cognitive Level: Applying

Client Need: Physiological Integrity

Page Number: 414

Nursing/Integrated Concepts: Nursing Process: Implementation

Learning Outcome: 26-5 Explain the need for immunosuppressant medications following organ transplants and for treating severe inflammation.

Question 7

Type: MCSA

A client has been prescribed an immunosuppressant. The client asks the nurse, “Which of my medications is an immunosuppressant?” What is the most appropriate response by the nurse?

1. Ibuprofen (Motrin)
2. Cortisone (Cortone)
3. Cyclosporine (Neoral)
4. Prednisone

Cognitive Level: Applying

Client Need: Physiological Integrity

Page Number: 414

Nursing/Integrated Concepts: Nursing Process: Implementation

Learning Outcome: 26-5 Explain the need for immunosuppressant medications following organ transplants and for treating severe inflammation.

Question 8

Type: MCSA

A nurse is teaching her client about cyclosporine therapy following a recent liver transplant. What statement by the client indicates further teaching is needed?

1. “I might experience a decrease in urinary flow.”
2. “I can take ibuprofen (Advil) for a headache, but I have to be very careful.”
3. “I can take this drug with any fluid as long as it is at the same time every day.”
4. “I will need to come into the clinic for periodic blood counts.”

Cognitive Level: Applying

Client Need: Physiological Integrity

Page Number: 415

Nursing/Integrated Concepts: Nursing Process: Implementation

Learning Outcome: 26-5 Explain the need for immunosuppressant medications following organ transplants and for treating severe inflammation.

Question 9

Type: MCSA

A client received the hepatitis B vaccine as per job policy. The nurse teaches the client that the vaccine provides prophylaxis against exposure to the hepatitis B virus. How is the virus transmitted?

1. Water
2. Food
3. Germs
4. Blood

Cognitive Level: Understanding

Client Need: Physiological Integrity

Page Number: 410

Nursing/Integrated Concepts: Nursing Process: Implementation

Learning Outcome: 26-3 Explain the types of vaccines and how they are used to prevent illness.

Question 10

Type: MCSA

Teaching parents the importance of maintaining up-to-date vaccinations is a responsibility of the nurse. What is the primary goal of vaccinations a nurse should stress?

1. Vaccinations treating illness.
2. The school nurse is the only nurse responsible for vaccine education.
3. Health departments have a responsibility to support vaccine administration.
4. Long-term immunity is the intent of vaccines.

Cognitive Level: Applying

Client Need: Physiological Integrity

Page Number: 409

Nursing/Integrated Concepts: Nursing Process: Implementation

Learning Outcome: 26-2 Compare and contrast the humoral and cell-mediated immune responses.

Question 11

Type: MCSA

A client is diagnosed with leukemia. What should the nurse teach this client regarding vaccinations?

1. They are critical for survival.
2. They are the cause of the leukemia.
3. They are contraindicated because of a weak immune system.
4. They are too late.

Cognitive Level: Applying

Client Need: Physiological Integrity

Page Number: 410

Nursing/Integrated Concepts: Nursing Process: Implementation

Learning Outcome: 26-3 Explain the types of vaccines and how they are used to prevent illness.

Question 12

Type: MCSA

The nurse is caring for a client who is prescribed biologic response modifiers to boost the immune response for renal cell carcinoma. Which medication does the nurse expect to find on the medication administration record (MAR)?

1. Aldesleukin (Proleukin)
2. Anakinra (Kineret)
3. Azathioprine (Azasan)
4. Basiliximab (Simulect)

Cognitive Level: Applying

Client Need: Physiological Integrity

Page Number: 412

Nursing/Integrated Concepts: Nursing Process: Assessment

Learning Outcome: 26-4 Identify indications for pharmacotherapy with biologic response modifiers.

Question 13

Type: MCSA

The nurse is teaching a client about immunity and discussing adaptive body defenses. Which cells are responsible for the functions of the immune response?

1. B cells

2. Cytokines

3. Lymphocytes

4. Activated T cells

Cognitive Level: Understanding

Client Need: Physiological Integrity

Page Number: 408

Nursing/Integrated Concepts: Nursing Process: Planning

Learning Outcome: 26-1 Compare and contrast innate and adaptive body defenses.