Cell Differentiation & Stem Cells Test Bank Ch.8 6th Edition - Principles of Development 6e | Instructor Test Bank by Lewis Wolpert. DOCX document preview.
Type: multiple choice question
Title: Chapter 08 - Question 01
01) Which of the following is not associated with terminal differentiation?
a. Cells assume specific shapes associated with function
b. It is often controlled by master regulatory genes
c. Differentiated cells are highly proliferative
d. Cell fate is controlled by a specific combinations of genes
Type: multiple choice question
Title: Chapter 08 - Question 02
02) Which of the following is not true of epigenetic control?
a. It hinges on the methylation status of DNA
b. It refers to changes in the DNA nucleotide sequence
c. It involves post-translational modifications to histone proteins
d. The pattern of modifications on chromatin can be transmitted to daughter cells.
Type: multiple choice question
Title: Chapter 08 - Question 03
03) What is the correct flow of skeletal muscle development in a vertebrate embryo?
a. Myotome – myoblast – myotube – muscle fiber
b. Myoblast – myotome – myotube – muscle fiber
c. Myotome – myoblast – muscle fiber - myotube
d. Myotome – myotube – myoblast – muscle fiber
Type: multiple choice question
Title: Chapter 08 - Question 04
04) Which of the following is not true of the MyoD protein?
a. It promotes downstream muscle-specific transcription factors
b. It promotes its own production in a positive-feedback loop
c. Mouse knock-outs lacking MyoD function do not develop skeletal muscle
d. It is only expressed in muscle precursors and muscle cells
Type: multiple choice question
Title: Chapter 08 - Question 05
05) Which of the following surrounds a stem cell and maintains its proliferative state and self-renewal capabilities?
a. Stem-cell niche
b. Stem-cell milieu
c. Stem-cell marrow
d. Stem-cell complex
Type: multiple choice question
Title: Chapter 08 - Question 06
06) Which of the options given is the DNA control region that regulates switching in the beta-family globin genes during development?
a. Globin control region
b. Locus enhancer region
c. Globin activation region
d. Locus control region
Type: multiple choice question
Title: Chapter 08 - Question 07
07) Epidermal skin stem cells reside within the basal layer of the epidermis, just above the basement membrane and the dermis. What is the stem-cell niche for these particular stem cells?
a. The basement membrane
b. Neighbouring epidermal cells
c. Sebaceous glands
d. Sweat glands
Type: multiple choice question
Title: Chapter 08 - Question 08
08) The epithelial lining of the small intestine is exposed to a harsh environment and undergoes continuous cell loss. In which region of the small intestine do stem cells reside?
a. The goblet
b. The villus
c. The mesenchyme
d. The crypt
Type: multiple choice question
Title: Chapter 08 - Question 09
09) From which group of cells are embryonic stem cells derived?
a. Trophectoderm
b. Primitive endoderm
c. Extra-embryonic ectoderm
d. Inner cell mass
Type: multiple choice question
Title: Chapter 08 - Question 10
10) Which of the following is not true of somatic cell nuclear transfer?
a. It is used to produce animal clones
b. A nucleus from an adult differentiated cell is often used
c. It can be used to create patient-specific stem cells
d. The resulting embryo is genetically identical to the egg donor
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Principles of Development 6e | Instructor Test Bank
By Lewis Wolpert